Methotrexate

Methotrexate is used in the treatment of rheumatoid arthritis and psoriasis.

Methotrexate is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of the body's immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.

Abdominal pain, Loss of appetite, Nausea, Vomiting, Increased liver enzymes, Stomatitis (Inflammation of the mouth), Low blood platelets, Headache, Mouth ulcer, Decreased white blood cell count, Fatigue, Diarrhea, Drowsiness, Throat ulcer, Dyspepsia, Anemia (low number of red blood cells), Pneumonitis, Exanthema, Erythema (skin redness), Itching