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Actorise 40 Injection

Original price was: ₹2,928.20.Current price is: ₹2,635.38.

 Prescription Required

Salt : Darbepoetin alfa (40mcg)

Manufacturer : Cipla Ltd

Packing : 4 ml in 1 prefilled syringe

Description

PRODUCT INTRODUCTION

Actrise 40 Injection is a medication that falls under the category of erythropoiesis-stimulating agents (ESAs). It is a synthetic form of erythropoietin, a hormone produced naturally in the kidneys, which stimulates the production of red blood cells in the bone marrow. Actrise 40 Injection is formulated to treat anemia associated with chronic kidney disease (CKD) in adult patients who are undergoing dialysis. It is available in injectable form and is administered either intravenously or subcutaneously under the supervision of a healthcare professional.

USES OF ACTRISE 40 INJECTION

Actrise 40 Injection is primarily prescribed for the management of anemia in patients with chronic kidney disease who are on dialysis. Anemia is a common complication of CKD, characterized by a decrease in the number of red blood cells or hemoglobin levels in the blood. Actrise 40 Injection works by stimulating the bone marrow to produce more red blood cells, thereby improving the oxygen-carrying capacity of the blood and alleviating symptoms associated with anemia such as fatigue, weakness, and shortness of breath.

BENEFITS OF ACTRISE 40 INJECTION

The administration of Actrise 40 Injection offers several benefits to patients suffering from anemia due to chronic kidney disease:

  • Improved Quality of Life: By increasing the production of red blood cells, Actrise 40 Injection helps alleviate symptoms of anemia such as fatigue and weakness, thereby improving the overall quality of life for patients undergoing dialysis.
  • Reduced Need for Blood Transfusions: Actrise 40 Injection reduces the dependence on blood transfusions, which are often required to manage severe anemia in patients with chronic kidney disease. This can minimize the risk of complications associated with transfusions and improve patient outcomes.
  • Enhanced Exercise Tolerance: By improving oxygen delivery to tissues and organs, Actrise 40 Injection can enhance exercise tolerance and physical endurance in patients with anemia, allowing them to engage in daily activities with greater ease.
  • Potential Cardiovascular Benefits: Adequate treatment of anemia with Actrise 40 Injection may help reduce the risk of cardiovascular complications associated with chronic kidney disease, such as heart failure and myocardial infarction, by optimizing oxygen delivery to the heart and other vital organs.

SIDE EFFECTS OF ACTRISE 40 INJECTION

While Actrise 40 Injection can be effective in managing anemia associated with chronic kidney disease, it is essential to be aware of potential side effects that may occur with its use. Common side effects of Actrise 40 Injection may include:

  • Hypertension (high blood pressure): Actrise 40 Injection can sometimes cause an increase in blood pressure, which may require monitoring and management with antihypertensive medications.
  • Headache: Some patients may experience headaches as a side effect of Actrise 40 Injection, which is usually mild to moderate in severity and resolves with time.
  • Injection Site Reactions: Pain, redness, or swelling at the injection site are common side effects of Actrise 40 Injection when administered subcutaneously. Rotating injection sites and using proper injection techniques can help minimize these reactions.
  • Flu-like Symptoms: Some patients may experience flu-like symptoms such as fever, chills, and body aches following the administration of Actrise 40 Injection. These symptoms are usually transient and resolve on their own without specific treatment.
  • Blood Clots: In some cases, Actrise 40 Injection may increase the risk of blood clots, particularly in patients with a history of cardiovascular disease or other risk factors for thromboembolic events. It is essential to monitor patients closely for signs of thrombosis and take appropriate preventive measures.

References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
  3. Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  4. Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. [Accessed 07 Apr. 2019] (online) Available from:External Link
  5. CiplaMed. Darbepoetin Alfa [Product Information]. [Last Reviewed: June 2019]. [Accessed 17 Jun. 2023] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Darbepoetin. [Accessed 17 Jun. 2023] (online) Available from:External Link
  7. Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019. [Accessed 17 Jun. 2023] (online) Available from:External Link
  8. Aranesp Injection (Darbepoetin alfa) [Product Information]. [Accessed 17 Jun. 2023] (online) Available from:External Link

Disclaimer

Singhla Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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Shipping & Delivery

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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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