Advacan 0.25mg Tablet

PRODUCT INTRODUCTION

Advacan 0.25mg Tablet is a pharmaceutical product that contains Everolimus, a potent immunosuppressant and anti-proliferative agent. Everolimus belongs to a class of medications known as mTOR inhibitors (mammalian target of rapamycin inhibitors). These inhibitors play a crucial role in regulating cell growth, proliferation, and survival. Advacan is primarily used in the management of various conditions where immunosuppression or reduction in cell proliferation is beneficial.

The tablet is specifically designed for oral administration, offering a convenient and effective means for patients to manage their conditions. The precise formulation and dosage of Advacan 0.25mg allow for a controlled and steady release of Everolimus, ensuring optimal therapeutic outcomes while minimizing potential side effects.

USES OF Advacan 0.25mg TABLET

Advacan 0.25mg Tablet is prescribed for several critical medical conditions, including:

• Prevention of Organ Rejection: Post-transplant, the body’s immune system might reject the new organ (such as kidney or liver). Advacan helps suppress the immune response to prevent this rejection, ensuring the longevity and function of the transplanted organ.
• Cancer Treatment: Advacan is utilized in the treatment of various cancers, such as advanced renal cell carcinoma (kidney cancer), hormone receptor-positive breast cancer, neuroendocrine tumors, and tuberous sclerosis complex-related subependymal giant cell astrocytoma (SEGA). It works by inhibiting the proliferation of cancer cells, thus slowing down tumor growth.
• Treatment of Tuberous Sclerosis Complex (TSC): This genetic disorder can lead to the growth of benign tumors in various organs. Advacan helps manage TSC by reducing the growth and proliferation of these tumors.

BENEFITS OF Advacan 0.25mg TABLET

Advacan offers multiple therapeutic benefits, making it a valuable medication in various clinical scenarios:

• Effective Immunosuppression: By inhibiting the mTOR pathway, Advacan provides robust immunosuppression, essential for patients who have undergone organ transplantation. It helps in preventing acute and chronic rejection episodes, thus improving transplant success rates.
• Cancer Management: In oncology, Advacan’s ability to slow down the proliferation of cancer cells translates into better disease control and potentially prolonged survival in patients with advanced malignancies. Its role in combination with other therapies enhances the overall effectiveness of cancer treatment regimens.
• Management of TSC-Related Tumors: For patients with tuberous sclerosis complex, Advacan reduces the size and growth of benign tumors, improving the quality of life and reducing complications associated with the disease.
• Convenience and Compliance: The oral tablet form of Advacan ensures ease of administration, promoting better patient adherence to the treatment regimen.

SIDE EFFECTS OF Advacan 0.25mg TABLET

While Advacan 0.25mg Tablet is beneficial in managing various conditions, it is also associated with a range of potential side effects. It is important for patients and healthcare providers to be aware of these to manage them effectively:

• Common Side Effects: Patients may experience mouth ulcers, stomatitis (inflammation of the mouth), infections, increased blood sugar levels (hyperglycemia), fatigue, diarrhea, nausea, and decreased appetite. These side effects are usually manageable with supportive care and dose adjustments.
• Serious Side Effects: Some patients might develop severe infections due to the immunosuppressive nature of the drug. Pneumonitis (inflammation of lung tissue), kidney dysfunction, and elevated cholesterol and triglyceride levels are notable concerns. Monitoring and preventive measures are essential to mitigate these risks.
• Hematologic Side Effects: Everolimus can cause cytopenias, including anemia (low red blood cells), thrombocytopenia (low platelets), and neutropenia (low white blood cells), which can increase the risk of infections and bleeding. Regular blood tests are crucial to detect and manage these conditions early.
• Allergic Reactions: Although rare, some patients might experience hypersensitivity reactions, such as rash, itching, and swelling. Severe allergic reactions (anaphylaxis) require immediate medical attention.
• Long-term Use Concerns: Chronic use of Advacan might be associated with delayed wound healing, increased risk of skin cancers, and other malignancies. Long-term monitoring and regular check-ups are vital to detect any adverse effects early.

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