Abiratas 250mg Tablet
Abiratas 250mg Tablet Original price was: ₹30,193.00.Current price is: ₹14,000.00.
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Abitate U 250mg Tablet
Abitate U 250mg Tablet Original price was: ₹36,286.08.Current price is: ₹11,000.00.

Ahabir 250mg Tablet

Original price was: ₹33,000.00.Current price is: ₹10,500.00.

 Prescription Required

Salt : Abiraterone Acetate

Manufacturer : Hetero Healthcare Ltd

Packing : 120 tablets in 1 bottle

Description

Product Introduction

Ahabir 250mg Tablet is a notable pharmaceutical used in the treatment of prostate cancer. This medication is specifically formulated to contain abiraterone acetate, a potent inhibitor of CYP17 (17α-hydroxylase/C17,20-lyase), an enzyme that plays a critical role in the production of androgens (male hormones) in the testes, adrenal glands, and prostate tumor tissue. By inhibiting this enzyme, Ahabir effectively reduces the levels of androgens that can stimulate the growth of prostate cancer cells.

Ahabir 250mg Tablets are typically administered as part of a combined therapeutic regimen that includes a corticosteroid, such as prednisone, to mitigate potential side effects related to elevated levels of adrenocorticotropic hormone (ACTH) due to CYP17 inhibition. This medication is available in tablet form and is generally prescribed to be taken once daily on an empty stomach. It is crucial not to consume food two hours before and one hour after taking Ahabir to enhance its absorption and efficacy.

Uses of Ahabir 250mg Tablet

Ahabir 250mg Tablet is primarily used in the management of metastatic castration-resistant prostate cancer (mCRPC), which is a form of prostate cancer that continues to progress despite the lowering of testosterone levels to very low, or “castrate,” levels. It is effective in patients who have not responded adequately to previous chemotherapy regimens that included docetaxel.

The action of Ahabir, through the inhibition of androgen production, helps in decreasing the proliferation of cancer cells, thereby slowing the progression of the disease and potentially enhancing the quality of life and survival of affected individuals. Additionally, Ahabir is sometimes used in treating metastatic high-risk castration-sensitive prostate cancer, expanding its utility in various stages of prostate cancer treatment.

Benefits of Ahabir 250mg Tablet

The primary benefit of Ahabir 250mg Tablet lies in its ability to significantly reduce the progression of prostate cancer in men whose disease has advanced despite receiving hormone therapy. The medication has been shown to extend overall survival rates and delay the progression of symptoms associated with the disease, such as pain and physical discomfort, thus improving the patient’s quality of life.

Clinical trials have demonstrated that patients treated with Ahabir have experienced a delay in the progression of their cancer, reduced tumor burden, and a decreased need for pain medication compared to those who did not receive this treatment. Furthermore, Ahabir offers a treatment alternative for patients who may not be candidates for chemotherapy due to its associated toxicity or for those who have previously exhibited resistance to chemotherapy.

Side Effects of Ahabir 250mg Tablet

While Ahabir 250mg Tablet offers substantial benefits in treating prostate cancer, it also comes with a range of potential side effects. The most common side effects include but are not limited to hypertension, fluid retention or edema, hypokalemia (low potassium levels in the blood), fatigue, and hepatic enzyme elevation. These effects are manageable with appropriate medical supervision and adjustments to the treatment regimen.

More serious adverse effects may include severe hypertension, adrenal insufficiency, hepatotoxicity, and cardiac complications, which require prompt medical intervention. Patients are regularly monitored through blood tests to check liver function, potassium levels, and other indicators of health to mitigate these risks effectively.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
  2. Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Disclaimer

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