PRODUCT INTRODUCTION
Azithral 250mg DT Tablet is an antibiotic medication that belongs to a class of drugs known as macrolide antibiotics. It is primarily used to treat various bacterial infections by inhibiting the growth and multiplication of bacteria. This medication is available in a dispersible tablet form and contains 250 mg of azithromycin, the active ingredient. Azithral 250mg DT is typically prescribed to treat respiratory infections, skin infections, ear infections, and sexually transmitted diseases among others.
Azithromycin, the key ingredient, works by binding to the 50S ribosomal subunit of the bacterial ribosome, thus inhibiting the translation of mRNA. This action prevents the bacteria from growing and reproducing, effectively treating the infection. Azithral tablets are known for their efficacy and are commonly prescribed because they allow for short treatment durations, typically five days or less.
USES of Azithral 250mg DT Tablet
Azithral 250mg DT is utilized to manage a variety of bacterial infections. Here are some of the primary uses:
- Respiratory Tract Infections: It is effective in treating infections of the upper and lower respiratory tract such as bronchitis, pneumonia, tonsillitis, and sinusitis.
- Skin and Soft Tissue Infections: Used for treating conditions like impetigo, dermatitis, and cellulitis.
- Ear Infections: It helps in managing otitis media and other ear-related bacterial ailments.
- Sexually Transmitted Diseases: Azithral is often prescribed for the treatment of sexually transmitted infections like chlamydia and gonorrhea.
- Others: It can also be used to treat certain types of diarrheal infections and community-acquired infections.
BENEFITS OF Azithral 250mg DT Tablet
The benefits of using Azithral 250mg DT are tied closely to its broad spectrum of action against bacteria. Some of the significant benefits include:
- Broad Spectrum: Effective against a wide variety of bacteria, which makes it a preferred choice in the treatment of mixed infections.
- Convenient Dosing Schedule: Typically, Azithral requires a shorter course of treatment, often completed in 3 to 5 days, unlike other antibiotics that might need longer durations.
- Good Tolerability: Azithral is generally well tolerated by patients, with a low incidence of severe side effects.
- Effective in Penicillin-Allergic Patients: A viable alternative for patients who are allergic to penicillin.
- Flexibility of Administration: The dispersible tablet form can be easily administered, especially in patients who have difficulty swallowing pills.
SIDE EFFECTS OF Azithral 250mg DT Tablet
While Azithral 250mg DT is effective and safe for most individuals, some may experience side effects. Common side effects include:
- Gastrointestinal Issues: Nausea, vomiting, diarrhea, and abdominal pain are the most common side effects, largely due to the gastrointestinal action of the drug.
- Headache and Dizziness: Some individuals might experience headaches or dizziness during the course of treatment.
- Taste Disturbances: A change in taste sensation or a metallic taste is occasionally reported by patients.
- Fatigue: Feeling unusually tired or fatigued is another potential side effect.
Less commonly, more serious side effects can occur, such as:
- Allergic Reactions: Rash, itching, or even more severe reactions like anaphylaxis, although rare, can occur.
- Cardiac Effects: Heart rhythm changes like QT prolongation have been associated with azithromycin, particularly in patients with existing heart conditions.
- Liver Dysfunction: Elevated liver enzymes, jaundice, or hepatotoxicity are rare but possible.
References
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Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 801.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 117-20.
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