Biotrexate 15mg Injection

Product Introduction

Biotrexate 15mg Injection is a crucial medicinal formulation used primarily in the treatment of various severe and chronic conditions. Containing Methotrexate as its active ingredient, this medication belongs to the class of drugs known as antimetabolites. Methotrexate interferes with the growth of certain cells of the body, particularly cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Uses of Biotrexate 15mg Injection

Biotrexate 15mg Injection is employed in a range of therapeutic settings:

1. Cancer Treatment: It is most commonly used to treat certain types of cancer such as breast cancer, leukemia, lung cancer, and osteosarcoma. By inhibiting the DNA synthesis in cancer cells, it prevents their proliferation and spread.
2. Autoimmune Diseases: Methotrexate is also a cornerstone in the management of several autoimmune diseases including rheumatoid arthritis, where it reduces the immune system’s harmful attacks on the joints, and psoriasis, which is marked by overactive skin cell production.
3. Ectopic Pregnancy: In early non-surgical management of ectopic pregnancy, Methotrexate can be used to stop the growth of embryonic cells in the fallopian tube, thereby avoiding the need for surgical intervention.

Benefits of Biotrexate 15mg Injection

The administration of Biotrexate 15mg Injection offers several benefits across its diverse indications:

• Cancer Control: For cancer patients, Biotrexate can be a part of a combination therapy to help reduce tumor size and prevent the spread of cancer, thus potentially enhancing survival rates and quality of life.
• Symptom Management in Autoimmune Disorders: Patients suffering from conditions like rheumatoid arthritis and psoriasis often experience significant symptom relief with Methotrexate. It helps reduce pain, swelling, and can improve physical function in rheumatoid arthritis, and decreases the rate of skin cell turnover in psoriasis, easing red patches.
• Preservation of Fertility: By treating ectopic pregnancies with Methotrexate, it helps preserve the future fertility of the patient by potentially avoiding invasive surgeries that might impact the reproductive organs.

Side Effects of Biotrexate 15mg Injection

While Biotrexate 15mg Injection is beneficial for many patients, it does come with a risk of side effects. These can range from mild to severe and include:

• Common Side Effects: Nausea, vomiting, and abdominal pain are frequently reported. Sores in the mouth and lips, fatigue, and dizziness are also common. These side effects often resolve without the need for discontinuation of therapy.
• Blood-Related Issues: As Methotrexate can affect bone marrow function, there might be a decrease in the number of white blood cells, which increases the risk of infection, or a decrease in the number of platelets, which can lead to bruising and bleeding.
• Liver and Kidney Impairment: Long-term use of Methotrexate can lead to liver fibrosis or cirrhosis, and it may also affect kidney function. Regular monitoring of liver and kidney function is recommended for patients on long-term therapy.
• Respiratory Effects: Some patients may experience lung problems, such as dry cough or shortness of breath. This requires immediate medical attention as it might indicate a potentially serious condition like pneumonitis.
• Teratogenic Effects: Methotrexate is known to cause fetal harm when administered to a pregnant woman and can lead to congenital abnormalities. Effective contraception must be used by both male and female patients during treatment and for a period after cessation of therapy.