Biovorin 15mg Injection

Product Introduction

Biovorin 15mg Injection is a pivotal medication primarily utilized in the field of oncology. Its active ingredient, calcium folinate, is a form of folinic acid, which plays a crucial role in biochemical processes involving folate. Manufactured as a sterile, preservative-free solution, Biovorin is packaged for intravenous or intramuscular injection. This medication serves as a crucial agent in both the enhancement of chemotherapeutic efficacy and the mitigation of certain side effects associated with cancer treatment protocols.

Uses of Biovorin 15mg Injection

Biovorin 15mg Injection is used in several critical therapeutic areas:

1. Antidote to Folate Antagonist Toxicity: Biovorin is frequently employed to diminish the toxic effects of methotrexate, a folate antagonist used in high doses for treating certain cancers, such as osteosarcoma. Biovorin acts by replenishing the body’s folate reserves, which are depleted by methotrexate and other drugs that inhibit dihydrofolate reductase.
2. Enhancing Chemotherapy Efficacy: In combination with 5-fluorouracil, a chemotherapeutic agent, Biovorin is used to treat colorectal cancer. It enhances the cytotoxic effect of 5-fluorouracil by stabilizing the bond between the drug and its target enzyme, thymidylate synthase, increasing its anti-tumor activity.
3. Treatment of Megaloblastic Anemias: Biovorin is also prescribed for the treatment of megaloblastic anemias due to folate deficiency. These anemias are often seen in conditions such as pregnancy, malabsorptive disorders, or in the context of excessive alcohol consumption.

Benefits of Biovorin 15mg Injection

The primary benefits of Biovorin 15mg Injection are its ability to counteract drug toxicity and enhance chemotherapy efficacy, which can be critical in a patient’s cancer treatment journey. By mitigating the side effects of potent chemotherapeutic agents, Biovorin helps in maintaining the necessary dosage and regimen of chemotherapy, ensuring optimal treatment efficacy. Moreover, by aiding in the recovery from megaloblastic anemias, Biovorin helps improve the overall hematological health of patients, which can be crucial for those undergoing intensive cancer therapies.

Side Effects of Biovorin 15mg Injection

While Biovorin 15mg Injection is generally well-tolerated, it can cause some side effects, which vary depending on the individual and their overall health condition. Common side effects include:

• Allergic Reactions: Some patients may experience allergic reactions to Biovorin, symptoms of which can include rash, itching, swelling, dizziness, and trouble breathing.
• Gastrointestinal Issues: Nausea, vomiting, and diarrhea can occur, although these are typically mild and manageable.
• Neurological Effects: Rarely, patients may experience insomnia or agitation following the administration of Biovorin.
• Fever and Chills: These symptoms can occasionally be observed, but they are generally transient.