PRODUCT INTRODUCTION
Bosentas 125mg Tablet is a medication primarily used in the treatment of pulmonary arterial hypertension (PAH). It belongs to a class of drugs known as endothelin receptor antagonists. Manufactured by reputable pharmaceutical companies, Bosentas is available in various dosages, with the 125mg variant being one of the commonly prescribed strengths.
The active ingredient in Bosentas tablets is Bosentan, which exerts its therapeutic effects by blocking the action of endothelin, a substance in the body that narrows blood vessels and contributes to high blood pressure in the lungs. By inhibiting endothelin receptors, Bosentas helps dilate pulmonary blood vessels, thereby reducing the workload on the heart and improving blood flow to the lungs.
USES of Bosentas 125mg Tablet
Bosentas 125mg Tablet is primarily prescribed for the treatment of pulmonary arterial hypertension (PAH). PAH is a progressive and debilitating condition characterized by high blood pressure in the arteries that supply blood to the lungs. This increased pressure in the pulmonary arteries can lead to symptoms such as shortness of breath, fatigue, chest pain, and fainting spells. If left untreated, PAH can significantly impair a person’s quality of life and lead to life-threatening complications.
Bosentas 125mg Tablet helps manage PAH by improving exercise capacity and slowing down disease progression. It is often prescribed as part of a comprehensive treatment regimen that may include other medications, lifestyle modifications, and supportive therapies. Your healthcare provider will determine the appropriate dosage and treatment duration based on your individual medical history and response to therapy.
BENEFITS OF Bosentas 125mg Tablet
The benefits of Bosentas 125mg Tablet in the management of PAH are significant and multifaceted:
- Improved Exercise Tolerance: Bosentas helps enhance exercise capacity by reducing pulmonary artery pressure and improving blood flow to the lungs. This enables individuals with PAH to engage in physical activities with less exertion and fatigue.
- Delayed Disease Progression: By targeting the underlying mechanisms of PAH, Bosentas can slow down disease progression and minimize the risk of worsening symptoms and complications over time.
- Enhanced Quality of Life: Effective management of PAH with Bosentas can lead to improvements in symptoms such as shortness of breath, fatigue, and chest pain, allowing patients to enjoy a better quality of life and participate more fully in daily activities.
- Reduced Hospitalizations: Studies have shown that treatment with Bosentas can reduce the frequency of hospitalizations and emergency room visits related to PAH exacerbations, thereby lowering healthcare costs and improving patient outcomes.
- Potential Survival Benefits: In some cases, Bosentas therapy may contribute to increased survival rates among individuals with PAH, particularly when used in conjunction with other PAH medications and appropriate medical care.
SIDE EFFECTS OF Bosentas 125mg Tablet
While Bosentas 125mg Tablet is generally well-tolerated, like any medication, it can cause side effects in some individuals. Common side effects associated with Bosentas may include:
- Headache
- Flushing
- Edema (swelling of the ankles, feet, or hands)
- Nasal congestion
- Abdominal pain
- Nausea
- Liver function abnormalities
- Decreased hemoglobin levels
- Anemia
References
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Barnes PJ. Pulmonary Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1059.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 154-56.
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