Cabozanib 40mg Tablet

PRODUCT INTRODUCTION

Cabozanib 40mg Tablet is a medication classified as a tyrosine kinase inhibitor (TKI) used in the treatment of certain types of cancer. Developed by pharmaceutical company, CaboBio, it contains Cabozantinib as its active ingredient. This targeted therapy works by inhibiting the action of specific enzymes called tyrosine kinases, which are involved in the growth and spread of cancer cells. Cabozanib 40mg Tablet is typically prescribed in cases of advanced renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer), and thyroid cancer. It is available in tablet form for oral administration.

USES OF Cabozanib 40mg Tablet

Cabozanib 40mg Tablet is primarily indicated for the treatment of:

a. Renal Cell Carcinoma (Kidney Cancer): Cabozanib is used as a first-line treatment for patients with advanced renal cell carcinoma, either alone or in combination with other therapies. It helps to slow down the progression of the disease and may also shrink tumors, thereby improving overall survival rates.

b. Hepatocellular Carcinoma (Liver Cancer): In cases where hepatocellular carcinoma has spread beyond the liver or cannot be treated with surgery, Cabozanib may be prescribed. It works by targeting specific pathways involved in the growth and spread of liver cancer cells.

c. Thyroid Cancer: Cabozanib is utilized in the treatment of advanced medullary thyroid cancer, a rare type of thyroid cancer that has spread to other parts of the body. It helps to inhibit the growth of cancer cells and may improve symptoms and quality of life for patients with this condition.

BENEFITS OF Cabozanib 40mg Tablet

The benefits of Cabozanib 40mg Tablet include:

a. Tumor Suppression: Cabozanib inhibits the activity of tyrosine kinases, which are involved in various signaling pathways crucial for cancer cell growth and survival. By targeting these pathways, Cabozanib helps to suppress tumor growth and may even cause regression of existing tumors.

b. Prolonged Survival: Clinical studies have shown that treatment with Cabozanib can lead to significantly prolonged progression-free survival and overall survival rates in patients with advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.

c. Symptom Relief: Cabozanib therapy often results in symptom relief and improved quality of life for cancer patients. This may include reduced pain, better control of symptoms related to the cancer itself, and improved overall well-being.

SIDE EFFECTS OF Cabozanib 40mg Tablet

While Cabozanib 40mg Tablet can be highly effective in treating certain types of cancer, it may also cause various side effects. Common side effects associated with Cabozanib therapy include:

a. Hypertension (High Blood Pressure): Cabozanib can cause an increase in blood pressure, which may require monitoring and management with antihypertensive medications.

b. Fatigue: Many patients experience fatigue or tiredness while taking Cabozanib. This can range from mild to severe and may affect daily activities.

c. Diarrhea: Diarrhea is a common side effect of Cabozanib therapy. It can range from mild to severe and may require treatment with antidiarrheal medications.

d. Hand-Foot Syndrome: Cabozanib may cause a condition known as hand-foot syndrome, characterized by redness, swelling, and pain on the palms of the hands and the soles of the feet.

e. Proteinuria: Cabozanib can lead to an increase in the level of protein in the urine, which may indicate kidney damage. Regular monitoring of kidney function is essential during treatment.

f. Gastrointestinal Effects: Other gastrointestinal side effects may include nausea, vomiting, loss of appetite, and abdominal pain.

It’s important for patients receiving Cabozanib therapy to communicate any side effects they experience to their healthcare provider promptly. In some cases, dose adjustments or additional medications may be necessary to manage side effects and ensure the continuation of treatment.