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Calutide 50 Tablet

Original price was: ₹484.96.Current price is: ₹436.46.

Prescription Required

Salt : Bicalutamide (50mg)

Manufacturer : Cipla Ltd

Packing : 10 tablets in 1 strip

Description

PRODUCT INTRODUCTION

Calutide 50 Tablet, an oral medication, belongs to a class of drugs known as antiandrogens. It contains the active ingredient bicalutamide, which works by blocking the action of androgens, male hormones such as testosterone. Developed primarily for the treatment of prostate cancer, Calutide 50 Tablet is prescribed as part of a combination therapy regimen. It inhibits the growth of cancer cells by interfering with the androgen receptors, thus impeding the stimulating effect of androgens on tumor growth. Manufactured by reputable pharmaceutical companies, Calutide 50 Tablet is available in the form of round, white, film-coated tablets, typically administered once daily orally.

USES OF Calutide 50 Tablet

a. Treatment of Prostate Cancer: Calutide 50 Tablet is primarily indicated for the treatment of prostate cancer. Prostate cancer is often androgen-dependent, meaning it relies on the presence of male hormones like testosterone for growth and proliferation. By antagonizing the androgen receptors, Calutide 50 Tablet impedes the growth-promoting effects of these hormones, thereby slowing down the progression of prostate cancer. It is commonly prescribed in combination with other medications or therapies such as surgical castration or luteinizing hormone-releasing hormone (LHRH) analogs.

b. Management of Hirsutism: In addition to its anticancer properties, Calutide 50 Tablet has been found to be effective in the management of hirsutism in women. Hirsutism is a condition characterized by excessive hair growth in areas where hair is normally absent or minimal, such as the face, chest, and back. This excessive hair growth is often attributed to increased androgen levels in women. By blocking the action of androgens, Calutide 50 Tablet helps reduce the growth of unwanted facial and body hair in women with hirsutism, thereby improving their cosmetic appearance and overall quality of life.

BENEFITS OF Calutide 50 Tablet

a. Efficacy in Prostate Cancer Management: Calutide 50 Tablet has demonstrated significant efficacy in the treatment of prostate cancer, particularly when used in combination with other standard therapies. Clinical studies have shown that Calutide 50 Tablet, when administered as part of a comprehensive treatment regimen, can effectively slow down disease progression, reduce tumor size, alleviate symptoms, and improve overall survival rates in patients with prostate cancer.

b. Well-Tolerated Treatment Option: Compared to other antiandrogen medications, Calutide 50 Tablet is generally well-tolerated by most patients. Its favorable safety profile makes it a preferred choice for long-term use in the management of prostate cancer. Common side effects such as hot flashes, decreased libido, and erectile dysfunction are usually mild to moderate in intensity and can be effectively managed with supportive care or dose adjustments.

c. Improvement in Hirsutism Symptoms: For women suffering from hirsutism, Calutide 50 Tablet offers a promising treatment option. By reducing the growth of excessive facial and body hair, Calutide 50 Tablet helps restore a more feminine appearance and enhances self-esteem and confidence in affected individuals. The improvement in hirsutism symptoms can significantly enhance the quality of life for women struggling with this condition.

SIDE EFFECTS OF Calutide 50 Tablet

While Calutide 50 Tablet is generally well-tolerated, like any medication, it may cause certain side effects in some individuals. Common side effects associated with the use of Calutide 50 Tablet include:

a. Hot Flashes: One of the most common side effects of Calutide 50 Tablet is hot flashes, characterized by sudden feelings of warmth, flushing, and sweating. These symptoms are similar to those experienced during menopause and are caused by hormonal changes induced by the medication. Hot flashes can range from mild to severe and may interfere with daily activities and quality of life.

b. Decreased Libido and Erectile Dysfunction: Calutide 50 Tablet can affect sexual function in men, leading to decreased libido and erectile dysfunction. These side effects may occur due to the suppression of androgen activity by the medication. While these effects are usually reversible upon discontinuation of treatment, they can cause distress and impact the sexual well-being of affected individuals.

c. Gastrointestinal Disturbances: Some individuals may experience gastrointestinal disturbances such as nausea, vomiting, diarrhea, or constipation while taking Calutide 50 Tablet. These side effects are typically mild and transient but may require symptomatic treatment or dose adjustments in some cases.

d. Breast Tenderness or Enlargement: In rare cases, Calutide 50 Tablet may cause breast tenderness or enlargement (gynecomastia) in men. This side effect occurs due to the antiandrogenic activity of the medication, which can disrupt the hormonal balance and lead to changes in breast tissue. While not usually harmful, gynecomastia may cause discomfort or embarrassment for some individuals.

e. Liver Toxicity: There have been reports of liver toxicity associated with the use of Calutide 50 Tablet, manifesting as elevated liver enzymes or hepatocellular injury. Patients taking Calutide 50 Tablet should undergo regular monitoring of liver function tests to detect any signs of liver damage early on. In cases of severe liver toxicity, discontinuation of the medication may be necessary.

References

  1. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1766.
  2. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 724.
  3. Bicalutamide. Sellersville, PA: TEVA Pharmaceutical; 1995 [revised Jun. 2009]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Bicalutamide. Capability Green: AstraZeneca UK; 2000 [revised 08 Feb. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  6. Bicalutamide [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2017. [Accessed 20 Feb. 2024] (online) Available from: External Link

Disclaimer

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Shipping & Delivery

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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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