Ceftum 500mg Tablet
Ceftum 500mg Tablet Original price was: ₹230.41.Current price is: ₹207.37.
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Celol Max Soft Gelatin Capsule
Celol Max Soft Gelatin Capsule Original price was: ₹400.00.Current price is: ₹360.00.

Celdaz 500mg Injection

Original price was: ₹517.50.Current price is: ₹465.75.

Prescription Required

Salt : Dacarbazine

Manufacturer : Celon Laboratories Ltd

Packing : 1 Vial(S)

Description

PRODUCT INTRODUCTION

Celdaz 500mg Injection is a medication primarily composed of ceftaroline fosamil, which is a prodrug that converts to active ceftaroline upon administration. Ceftaroline belongs to the cephalosporin class of antibiotics and exhibits bactericidal activity against a broad spectrum of gram-positive and gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae.

The injection is formulated for intravenous administration and is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of the following organisms: Staphylococcus aureus (including MRSA), Streptococcus pyogenes, Streptococcus agalactiae, Escherichia coli, Klebsiella pneumoniae, and Klebsiella oxytoca.

USES OF Celdaz 500mg Injection

Celdaz 500mg Injection is prescribed by healthcare providers to treat the following conditions:

  • Acute Bacterial Skin and Skin Structure Infections (ABSSSI): These infections include cellulitis, wound infections, and major abscesses. Celdaz is effective against both gram-positive and some gram-negative pathogens commonly implicated in these infections, providing a reliable treatment option.
  • Community-Acquired Pneumonia (CAP): In certain cases, Celdaz may be considered for the treatment of CAP caused by susceptible organisms, particularly in patients requiring intravenous therapy.
  • Methicillin-Resistant Staphylococcus aureus (MRSA) Infections: Due to its activity against MRSA, Celdaz is valuable in treating infections caused by this notoriously resistant bacterium, especially when other antibiotics may be less effective.

BENEFITS OF Celdaz 500mg Injection

  • Broad Spectrum Activity: Celdaz exhibits potent activity against a wide range of gram-positive and gram-negative bacteria, including multidrug-resistant organisms like MRSA.
  • Efficacy in Skin Infections: It is particularly effective in treating complex skin infections, where quick and effective treatment is crucial to prevent complications.
  • Clinical Versatility: The drug’s versatility allows it to be used in various clinical settings, from hospitals treating severe infections to outpatient clinics managing less severe cases.
  • Intravenous Administration: Being formulated for intravenous use ensures rapid delivery and absorption, making it suitable for patients needing immediate and intensive therapy.
  • Safety Profile: With proper administration and monitoring, Celdaz is generally well-tolerated, offering a favorable safety profile for patients.

SIDE EFFECTS OF Celdaz 500mg Injection

While Celdaz 500mg Injection is effective, it can also cause certain adverse effects. Common side effects observed during clinical trials and post-marketing surveillance include:

  • Gastrointestinal Disturbances: Nausea, vomiting, diarrhea, and abdominal pain are commonly reported side effects.
  • Injection Site Reactions: Pain, redness, swelling, or inflammation at the site of injection may occur.
  • Headache and Dizziness: Some patients may experience headaches or dizziness during or after administration.
  • Hematologic Effects: There can be changes in blood cell counts, such as leukopenia (reduced white blood cell count), thrombocytosis (increased platelet count), or transient eosinophilia.
  • Hepatic Abnormalities: Liver function tests may show abnormalities in some patients.
  • Renal Effects: Transient elevations in serum creatinine levels have been reported.
  • Hypersensitivity Reactions: Serious allergic reactions including anaphylaxis are rare but possible with cephalosporin antibiotics.
  • Clostridium difficile-associated Diarrhea: As with many antibiotics, Celdaz can disrupt normal gut flora and potentially lead to C. difficile-associated diarrhea, ranging from mild diarrhea to life-threatening colitis.

References

  1. Medac, [Revised on Jul 2020] [Accessed on 27th March 2023] https://www.hpra.ie/img/uploaded/swedocuments/1d9264f6-b924-4af9-9b27-af9c9593d4a3.pdf
  2. Hospira, Inc., [Revised on Apr 2021] [Accessed on 27th March 2023], http://labeling.pfizer.com/ShowLabeling.aspx?id=5938
  3. Devendra Choudhary, Hanmant Goykar, Dnyaneshwar Kalyane, Nagaraja Sreeharsha, Rakesh K.Tekade, Prodrug design for improving the biopharmaceutical properties of therapeutic drugs, The Future of Pharmaceutical Product Development and Research, 1st Edition, 2020, 179-226.
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Chemotherapy of neoplastic diseases, 12th edition, 2011, 1686 and 1687.
  5. Bertram.G.Katzung, Basic and Clinical Pharmacology, Cancer Chemotherapeutic drugs, 14th edition, 2017, 956.
  6. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 861.

Disclaimer

Singhla Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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