Clavix-AS 75 Tablet
Clavix-AS 75 Tablet Original price was: ₹92.00.Current price is: ₹82.80.
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Clavix Tablet

Original price was: ₹111.89.Current price is: ₹100.70.

Prescription Required

Salt : Clopidogrel (75mg)

Manufacturer : Intas Pharmaceuticals Ltd

Packing : 15 tablets in 1 strip

Description

Product Introduction

Clavix Tablet, containing the active ingredient clopidogrel, is an antiplatelet medication widely used to prevent blood clots in patients with certain cardiovascular conditions. Clopidogrel belongs to a class of drugs known as thienopyridines, which work by inhibiting platelet aggregation, thereby reducing the risk of heart attacks, strokes, and other cardiovascular events. This medication is often prescribed to patients who have experienced a recent heart attack or stroke, or those with established peripheral arterial disease or acute coronary syndrome. Clavix Tablet is usually taken orally, and its effectiveness can be influenced by individual patient characteristics, including genetic factors and concomitant medical conditions.

Uses of Clavix Tablet

Clavix Tablet is primarily used for:

  1. Prevention of Atherosclerotic Events: Clavix Tablet is indicated for the prevention of atherosclerotic events such as heart attacks and strokes in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.
  2. Acute Coronary Syndrome: For patients with acute coronary syndrome (ACS), including unstable angina or non-ST-elevation myocardial infarction (NSTEMI), Clavix Tablet is used in combination with aspirin to reduce the rate of cardiovascular death, myocardial infarction, or stroke.
  3. Percutaneous Coronary Intervention (PCI): Clavix Tablet is often prescribed following PCI, including those who have had a stent implanted, to prevent stent thrombosis and other thrombotic complications.
  4. Prevention of Thrombotic Events in Atrial Fibrillation: For patients with atrial fibrillation who are at risk for thromboembolic events but cannot take oral anticoagulants, Clavix Tablet in combination with aspirin can reduce the risk of stroke.

Benefits of Clavix Tablet

The primary benefits of Clavix Tablet are its ability to significantly reduce the risk of serious cardiovascular events by inhibiting platelet aggregation. Key benefits include:

  1. Reduced Risk of Heart Attack and Stroke: By preventing the formation of blood clots, Clavix Tablet effectively lowers the risk of heart attacks and strokes in patients with cardiovascular diseases.
  2. Enhanced Survival in ACS Patients: For patients with acute coronary syndrome, Clavix Tablet, especially when used with aspirin, can reduce mortality rates and improve long-term outcomes by preventing recurrent cardiovascular events.
  3. Improved Outcomes Post-PCI: In patients who have undergone percutaneous coronary intervention, Clavix Tablet helps prevent stent thrombosis, ensuring the success of the procedure and reducing the risk of complications.
  4. Stroke Prevention in Atrial Fibrillation: In patients with atrial fibrillation who are not suitable for oral anticoagulants, Clavix Tablet provides an alternative to reduce the risk of stroke.
  5. Convenience of Use: Clavix Tablet is taken orally, which makes it easy to administer and adhere to, especially when compared to injectable anticoagulants.

Side Effects of Clavix Tablet

While Clavix Tablet is generally well-tolerated, it can cause side effects in some patients. Common side effects include:

  1. Bleeding: The most significant risk associated with Clavix Tablet is bleeding. This can range from minor bleeding, such as bruising and nosebleeds, to more serious bleeding events like gastrointestinal bleeding or intracranial hemorrhage. Patients should be monitored for signs of bleeding and advised to report any unusual bleeding to their healthcare provider immediately.
  2. Gastrointestinal Issues: Some patients may experience gastrointestinal disturbances, including nausea, diarrhea, abdominal pain, and indigestion. Taking the medication with food can help mitigate these effects.
  3. Hematologic Effects: Rarely, Clavix Tablet can cause hematologic side effects such as thrombotic thrombocytopenic purpura (TTP), a serious condition characterized by low platelet counts, hemolytic anemia, and renal dysfunction. This condition requires immediate medical attention.
  4. Allergic Reactions: Although uncommon, allergic reactions to Clavix Tablet can occur, presenting as rash, itching, swelling, dizziness, or difficulty breathing. Patients experiencing these symptoms should seek medical attention promptly.
  5. Liver Function Changes: In rare instances, Clavix Tablet can affect liver function, leading to elevated liver enzymes. Regular monitoring of liver function tests is advisable in patients on long-term therapy.
  6. Other Side Effects: Other potential side effects include headache, dizziness, and joint pain. These are generally mild and transient.

References

  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 869-70.
  2. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 598-99.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 304-305.
  4. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 245-48.
  5. Clopidogrel bisulfate. New York, New York: Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership; 2006. [Accessed 15 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). Clopidogrel. [Accessed 15 Mar. 2019] (online) Available from:External Link
  7. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Clopidogrel. [Updated 2019 Jun 3]. [Accessed 17 Jun. 2023] (online) Available from:External Link
  8. Clopidogrel [Summary of Product Characteristics]. Rue de la Vierge, France: Sanofi Winthrop Industrie; 2022. [Accessed 17 Jun. 2023] (online) Available from:External Link

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Shipping & Delivery

Shipping Policy

We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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