PRODUCT INTRODUCTION
Clexane 40mg Injection is a medication belonging to the class of anticoagulants, specifically low molecular weight heparins. It is commonly prescribed to prevent blood clot formation in various medical conditions. Clexane works by inhibiting certain clotting factors in the blood, thereby reducing the risk of clot formation. It is typically administered via subcutaneous injection.
USES OF Clexane 40mg Injection
Clexane 40mg Injection is prescribed for several medical conditions, including:
- Prevention of blood clots in patients undergoing surgery, particularly orthopedic surgeries like hip or knee replacement.
- Treatment and prevention of blood clots in conditions such as deep vein thrombosis (DVT) and pulmonary embolism (PE).
- Management of unstable angina and non-Q-wave myocardial infarction in conjunction with aspirin.
BENEFITS OF Clexane 40mg Injection
- Effectively prevents the formation of blood clots, reducing the risk of serious complications such as stroke, heart attack, or pulmonary embolism.
- Offers convenient administration through subcutaneous injection.
- Has a predictable anticoagulant effect, allowing for effective management of thrombotic conditions.
- Suitable for various patient populations, including those undergoing surgery or with certain medical conditions requiring anticoagulation therapy.
SIDE EFFECTS OF Clexane 40mg Injection
While Clexane is generally well-tolerated, some individuals may experience side effects, which may include:
- Bleeding or bruising at the injection site.
- Allergic reactions such as rash, itching, or swelling.
- Rarely, severe bleeding or thrombocytopenia (reduced platelet count).
- Injection site hematoma (collection of blood under the skin).
- Elevations in liver enzymes or hyperkalemia (high potassium levels) in some cases.
It is important for patients to report any adverse effects to their healthcare provider promptly. Additionally, individuals with a history of bleeding disorders or those taking other blood-thinning medications should use Clexane with caution and under medical supervision.
References
- Rovi Biotech Limited, Electronic Medicines Compendium (EMC), [Revised on Nov 2018], [Accessed on 27th May 2023], https://www.medicines.org.uk/emc/files/pil.9330.pdf
- Sanofi, [Revised on Apr 2022] [Accessed on 27th May 2023], https://products.sanofi.us/lovenox/lovenox.pdf
- Clexane® syringes 100mg/ml solution for Injection – HPRA. [Revised on May 2022], [Accessed on 27th May 2023], https://www.hpra.ie/img/uploaded/swedocuments/7900ad74-3eb7-41a2-be4c-3b757cb841ec.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681.
Disclaimer
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