Prescription Required
Cold chainPRODUCT INTRODUCTION
Cresp 500 Injection is a medication primarily composed of Darbepoetin alfa, a synthetic form of erythropoietin. It is manufactured to stimulate the production of red blood cells in the body. Cresp 500 Injection is typically administered via injection and is prescribed under medical supervision.
USES OF Cresp 500 Injection
Cresp 500 Injection is commonly prescribed to manage anemia associated with chronic kidney disease (CKD), chemotherapy-induced anemia, and anemia caused by the use of certain medications. It is also indicated for treating anemia in patients with HIV infection, as well as those undergoing elective surgery to reduce the need for blood transfusions.
BENEFITS OF Cresp 500 Injection
- Stimulates red blood cell production: Cresp 500 Injection works by stimulating the bone marrow to produce more red blood cells, which helps alleviate symptoms associated with anemia such as fatigue, weakness, and shortness of breath.
- Improved quality of life: By increasing hemoglobin levels and improving oxygen delivery to tissues, Cresp 500 Injection can enhance patients’ overall quality of life by reducing symptoms of anemia and fatigue.
- Reduced need for blood transfusions: In patients undergoing chemotherapy or elective surgery, Cresp 500 Injection can reduce the need for blood transfusions by boosting red blood cell production, thereby minimizing the risks associated with transfusions.
SIDE EFFECTS OF Cresp 500 Injection
While Cresp 500 Injection is generally well-tolerated, it may cause some side effects in certain individuals. Common side effects may include:
- Headache
- Nausea
- Vomiting
- Diarrhea
- Muscle or joint pain
- Injection site reactions (pain, redness, swelling)
- High blood pressure (hypertension)
Serious side effects are rare but may include:
- Allergic reactions (rash, itching, swelling of the face, lips, or tongue, difficulty breathing)
- Seizures
- Stroke
- Heart attack
- Blood clots
- Worsening of hypertension
It is important to promptly report any unexpected or severe side effects to a healthcare professional. Additionally, patients should adhere to the prescribed dosage and follow their healthcare provider’s instructions closely while using Cresp 500 Injection.
References
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Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
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Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019. [Accessed 17 Jun. 2023] (online) Available from:
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