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Eptoin 300 ER Tablet

Original price was: ₹220.75.Current price is: ₹198.68.

Prescription Required

Salt : Eptoin 300 ER Tablet

Manufacturer : Abbott

Packing : 30 tablet er in 1 bottle

Description

Product Introduction

Eptoin 300 ER Tablet is a widely prescribed anticonvulsant medication that belongs to the class of drugs known as hydantoins. The active ingredient in Eptoin is Phenytoin, which has been used for many years to manage and treat various types of seizures. Phenytoin works by stabilizing the neuronal membrane, thereby reducing the excitability of nerve cells in the brain. This makes it particularly effective in controlling seizures in patients with epilepsy, a chronic neurological disorder characterized by recurrent, unprovoked seizures.

The “ER” in Eptoin 300 ER Tablet stands for “Extended Release,” which indicates that the medication is designed to release the active ingredient slowly over time. This allows for more consistent blood levels of Phenytoin, which can help in maintaining seizure control over an extended period and reduces the need for frequent dosing. Eptoin 300 ER Tablet is typically prescribed when lower doses of Phenytoin or immediate-release formulations are insufficient to control seizures effectively.

Uses of Eptoin 300 ER Tablet

Seizure Control: The primary use of Eptoin 300 ER Tablet is in the treatment and prevention of various types of seizures associated with epilepsy. It is particularly effective in managing generalized tonic-clonic seizures (formerly known as grand mal seizures) and complex partial seizures. These types of seizures involve loss of consciousness and convulsions, making them particularly disruptive and dangerous. Eptoin helps reduce the frequency and severity of these seizures, allowing patients to lead a more normal life.

Status Epilepticus: In some cases, Eptoin 300 ER Tablet may be used in the management of status epilepticus, a medical emergency characterized by prolonged or repeated seizures without recovery in between. While intravenous Phenytoin is typically used in acute settings, oral Eptoin may be prescribed for ongoing management after the acute episode has been controlled.

Neurosurgical Prophylaxis: Eptoin is also used prophylactically to prevent seizures following neurosurgery or traumatic brain injury. In such cases, it helps protect against post-surgical or injury-induced seizures, which can be a complication of these conditions.

Benefits of Eptoin 300 ER Tablet

Effective Seizure Control: One of the most significant benefits of Eptoin 300 ER Tablet is its efficacy in controlling various types of seizures. For patients with epilepsy, consistent and reliable seizure control is crucial for maintaining quality of life, reducing the risk of injury, and preventing the progression of the disorder. Eptoin is a well-established medication that has been used for decades, and its efficacy is supported by a wealth of clinical experience.

Extended Release Formulation: The extended-release formulation of Eptoin offers the advantage of steady drug levels in the blood, which can help in achieving better seizure control. This formulation is particularly beneficial for patients who require higher doses of Phenytoin, as it reduces the need for multiple daily doses and minimizes fluctuations in blood levels that can lead to breakthrough seizures or side effects.

Cost-Effective: Eptoin 300 ER Tablet is a cost-effective option for managing epilepsy, making it accessible to a wide range of patients. It is available as a generic medication, which further reduces the cost burden on patients and healthcare systems.

Versatility: Eptoin is versatile in its application, being useful in both the chronic management of epilepsy and in acute situations such as status epilepticus or post-neurosurgical seizure prophylaxis. This makes it a valuable medication in the neurologist’s arsenal.

Side Effects of Eptoin 300 ER Tablet

While Eptoin 300 ER Tablet is generally effective and well-tolerated, it can cause side effects in some patients. These side effects may vary in severity and can be dose-dependent.

Common Side Effects:

  • Dizziness and Drowsiness: These are among the most common side effects and are typically more pronounced when starting the medication or adjusting the dose. Patients are advised to avoid driving or operating heavy machinery until they know how the medication affects them.
  • Nausea and Vomiting: Gastrointestinal disturbances such as nausea and vomiting may occur, especially when the medication is taken on an empty stomach.
  • Gingival Hyperplasia: Long-term use of Eptoin can lead to overgrowth of the gums, a condition known as gingival hyperplasia. Good oral hygiene is important to minimize this risk.
  • Nystagmus: Involuntary eye movements (nystagmus) can occur with Eptoin use, particularly at higher doses.

Serious Side Effects:

  • Skin Reactions: Eptoin can cause serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis, which require immediate medical attention.
  • Bone Marrow Suppression: This can lead to a decrease in blood cell counts, increasing the risk of infections, bruising, and bleeding.
  • Liver Toxicity: Phenytoin can cause liver damage, which may present as jaundice, fatigue, or elevated liver enzymes in blood tests. Regular monitoring of liver function is recommended.
  • Cognitive and Behavioral Changes: In some cases, patients may experience mood changes, confusion, or memory problems, particularly at higher doses.

References

  1. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 591-93.
  2. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 403-405.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1111-116.
  4. Phenytoin. Cedex, France: Famar Orleans; 2018. [Accessed 22 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:External Link
  6. Phenytoin. New York, New York: Pfizer; 2009]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
  8. Phenytoin sodium [FDA Label]. Mumbai, India: Wockhardt Limited; 2007. [Accessed 28 Mar. 2023] (online) Available from: External Link
  9. Phenytoin [Prescribing Information]. New York, NY: Parke Davis; 2009. [Accessed 31 May 2024] (online) Available from: External Link

FAQ

Q1: Can Eptoin 300 ER Tablet be used during pregnancy? A1: Eptoin should be used during pregnancy only if the potential benefits outweigh the risks, as it can cause fetal harm. Pregnant women should consult their doctor to carefully weigh the risks and benefits and may need to adjust their treatment plan.

Q2: How should I take Eptoin 300 ER Tablet? A2: Eptoin 300 ER Tablet should be taken exactly as prescribed by your doctor. It is usually taken once daily, with or without food. Do not crush or chew the tablet, as it is designed to release the medication slowly.

Q3: What should I do if I miss a dose? A3: If you miss a dose of Eptoin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

Q4: Can I stop taking Eptoin 300 ER Tablet suddenly? A4: No, you should not stop taking Eptoin suddenly without consulting your doctor. Abrupt discontinuation can lead to increased seizure frequency or severity. Your doctor will guide you on how to taper the dose safely if discontinuation is necessary.

Q5: Are there any dietary restrictions while taking Eptoin? A5: There are no specific dietary restrictions while taking Eptoin, but it is recommended to maintain a balanced diet. Alcohol should be avoided as it can increase the risk of side effects and affect seizure control.


Disclaimer

Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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