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Evaparin 300mg Injection

Original price was: ₹3,527.25.Current price is: ₹1,950.00.

Prescription Required

Salt : Enoxaparin

Manufacturer : Intas Pharmaceuticals Ltd

Packing : 1 Prefilled Syringe(S) Of 3ml

Description

Product Introduction

Evaparin 300mg Injection is an anticoagulant medication primarily used to prevent and treat various thromboembolic disorders. The active ingredient in Evaparin is enoxaparin sodium, a low molecular weight heparin (LMWH). Enoxaparin works by inhibiting specific clotting factors in the blood, thereby reducing the risk of clot formation. This medication is commonly used in clinical settings such as hospitals and specialized medical facilities, often administered by healthcare professionals.

Evaparin 300mg is typically packaged in pre-filled syringes or vials for subcutaneous or intravenous administration. The convenience of pre-measured doses helps ensure accurate and consistent delivery of the medication. The injection is clear to slightly yellow in appearance and should be inspected for particulate matter or discoloration before use. The administration technique involves injecting the medication into the fatty layer just beneath the skin or directly into a vein, depending on the specific medical requirements of the patient.

Uses of Evaparin 300mg Injection

Evaparin 300mg Injection is utilized in a variety of clinical scenarios involving the prevention and treatment of blood clots. Key indications include:

  • Deep Vein Thrombosis (DVT): Evaparin is used to prevent and treat blood clots in the deep veins, typically in the legs, which can cause pain and swelling and may lead to serious complications if the clot dislodges and travels to the lungs.
  • Pulmonary Embolism (PE): This medication helps prevent and treat pulmonary embolism, a life-threatening condition where clots travel to the lungs, blocking blood flow and causing respiratory distress.
  • Myocardial Infarction (Heart Attack): Evaparin is administered to patients experiencing heart attacks to prevent further clot formation and reduce the risk of additional cardiac events.
  • Angina: For patients with unstable angina or non-ST-elevation myocardial infarction (NSTEMI), Evaparin helps stabilize the condition by preventing new clots from forming.
  • Surgical Prophylaxis: Post-surgical patients, especially those undergoing orthopedic procedures like hip or knee replacement, receive Evaparin to prevent the formation of blood clots during the recovery period.

Benefits of Evaparin 300mg Injection

The primary benefit of Evaparin 300mg Injection is its efficacy in preventing and treating potentially life-threatening thromboembolic disorders. Key benefits include:

  • Effective Anticoagulation: Evaparin provides reliable anticoagulation, reducing the risk of clot-related complications in high-risk patients.
  • Rapid Action: The medication quickly reaches therapeutic levels in the bloodstream, offering prompt protection against clot formation.
  • Ease of Use: Pre-filled syringes and clear dosing instructions make administration straightforward for healthcare providers.
  • Predictable Pharmacokinetics: Evaparin has a predictable effect on blood clotting, which helps in managing and adjusting dosages effectively based on patient response.
  • Reduced Monitoring Requirements: Compared to unfractionated heparin, Evaparin requires less frequent monitoring of clotting parameters, making it more convenient for both patients and healthcare providers.
  • Versatility in Clinical Use: It is suitable for a wide range of thromboembolic conditions, making it a versatile tool in anticoagulation therapy.

Side Effects of Evaparin 300mg Injection

While Evaparin 300mg Injection is highly effective, it can also cause side effects, some of which may require medical attention. Common side effects include:

  • Bleeding: The most significant risk with any anticoagulant is bleeding. This can range from minor bruising at the injection site to more serious internal bleeding. Signs of serious bleeding include unusual bruising, prolonged bleeding from cuts, blood in urine or stools, and coughing up or vomiting blood.
  • Injection Site Reactions: Patients may experience pain, redness, swelling, or irritation at the injection site. These reactions are usually mild and temporary.
  • Thrombocytopenia: A decrease in the number of platelets in the blood can occur, leading to an increased risk of bleeding. In rare cases, a serious immune-mediated condition called heparin-induced thrombocytopenia (HIT) can develop.
  • Allergic Reactions: Some patients may experience allergic reactions, which can manifest as rash, itching, swelling, dizziness, or trouble breathing. Severe allergic reactions require immediate medical attention.
  • Hematoma: Accumulation of blood under the skin at the injection site may occur, leading to a palpable lump and discomfort.
  • Osteoporosis (Long-term Use): Prolonged use of heparin products, including enoxaparin, has been associated with a decrease in bone density, potentially leading to osteoporosis and increased fracture risk.

References

  1. Rovi Biotech Limited, Electronic Medicines Compendium (EMC), [Revised on Nov 2018], [Accessed on 27th May 2023], https://www.medicines.org.uk/emc/files/pil.9330.pdf
  2. Sanofi, [Revised on Apr 2022] [Accessed on 27th May 2023], https://products.sanofi.us/lovenox/lovenox.pdf
  3. Clexane® syringes 100mg/ml solution for Injection – HPRA. [Revised on May 2022], [Accessed on 27th May 2023], https://www.hpra.ie/img/uploaded/swedocuments/7900ad74-3eb7-41a2-be4c-3b757cb841ec.pdf
  4. KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681.

Disclaimer

Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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