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Gibtulio 25mg Tablet

Original price was: ₹647.00.Current price is: ₹582.30.

Prescription Required

Salt : Empagliflozin (25mg)

Manufacturer : Lupin Ltd

Packing : 10 tablets in 1 strip

Description

Produkt Introduction

Gibtulio 25mg Tablet is a medication that contains the active ingredient Empagliflozin. Empagliflozin is a member of the class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. These medications are primarily used to manage blood sugar levels in individuals with type 2 diabetes mellitus. Manufactured by various pharmaceutical companies, Gibtulio 25mg Tablet is available by prescription and is often prescribed alongside diet and exercise to enhance glycemic control.

Empagliflozin, the active component of Gibtulio, functions by inhibiting the SGLT2 protein in the kidneys. This inhibition prevents glucose reabsorption into the bloodstream, thereby facilitating its excretion through urine. This unique mechanism not only helps reduce blood sugar levels but also contributes to weight loss and lower blood pressure, making it a comprehensive treatment option for type 2 diabetes.

Uses of Gibtulio 25mg Tablet

Gibtulio 25mg Tablet is primarily indicated for the management of type 2 diabetes mellitus. It is used as an adjunct to diet and exercise to improve glycemic control in adults. By lowering blood glucose levels, it helps prevent the long-term complications of diabetes, such as cardiovascular diseases, neuropathy, nephropathy, and retinopathy.

In addition to its glucose-lowering effects, Gibtulio 25mg Tablet has been shown to provide cardiovascular benefits. Studies have demonstrated that empagliflozin can reduce the risk of major cardiovascular events, including heart attack and stroke, in patients with type 2 diabetes who have existing cardiovascular disease. This makes it a valuable option for patients at high risk of cardiovascular complications.

Benefits of Gibtulio 25mg Tablet

  1. Effective Glycemic Control: Gibtulio 25mg Tablet effectively lowers blood sugar levels by promoting the excretion of glucose through urine. This helps in maintaining optimal glycemic control and reduces the risk of hyperglycemia-related complications.
  2. Weight Loss: One of the notable benefits of Gibtulio is its potential to aid in weight loss. By eliminating excess glucose from the body, it reduces caloric load, which can lead to modest weight reduction. This is particularly beneficial for overweight or obese patients with type 2 diabetes.
  3. Cardiovascular Protection: Empagliflozin has been associated with a reduction in cardiovascular events in patients with type 2 diabetes and established cardiovascular disease. This includes a lower risk of heart attacks, strokes, and cardiovascular mortality.
  4. Blood Pressure Reduction: Gibtulio also contributes to lowering blood pressure. The diuretic effect of increased glucose excretion leads to a reduction in blood volume, which helps in managing hypertension, a common comorbidity in diabetic patients.
  5. Renal Benefits: Empagliflozin has shown potential renal protective effects. It helps in slowing the progression of diabetic nephropathy by reducing albuminuria and preserving renal function, which is crucial for patients with diabetes-related kidney issues.

Side Effects of Gibtulio 25mg Tablet

While Gibtulio 25mg Tablet is generally well-tolerated, like any medication, it may cause side effects in some individuals. It is important to be aware of these potential adverse effects and to consult a healthcare provider if they occur.

  1. Genital Infections: The most common side effects of empagliflozin are genital mycotic infections, such as yeast infections in both men and women. Increased glucose in the urine creates a favorable environment for fungal growth.
  2. Urinary Tract Infections (UTIs): There is an increased risk of urinary tract infections with SGLT2 inhibitors. Symptoms may include frequent urination, pain during urination, and cloudy or foul-smelling urine.
  3. Dehydration: Due to the diuretic effect, Gibtulio can cause dehydration, which may lead to symptoms such as dizziness, lightheadedness, and increased thirst. It is essential to stay adequately hydrated while taking this medication.
  4. Ketoacidosis: Although rare, empagliflozin can increase the risk of diabetic ketoacidosis (DKA), a serious condition characterized by high levels of ketones in the blood. Symptoms include nausea, vomiting, abdominal pain, and confusion. Immediate medical attention is required if DKA is suspected.
  5. Hypoglycemia: When used in combination with other antidiabetic medications such as insulin or sulfonylureas, Gibtulio can increase the risk of hypoglycemia (low blood sugar). Symptoms include shakiness, sweating, confusion, and fainting.
  6. Increased Urination: As the medication works by promoting glucose excretion through urine, it can lead to increased frequency of urination, which may be inconvenient for some patients.
  7. Electrolyte Imbalance: The diuretic effect may also cause an imbalance in electrolytes, particularly sodium and potassium. Regular monitoring of electrolyte levels is recommended to avoid complications.

References

  1. Empagliflozin. Ridgefield, Connecticut; Boehringer Ingelheim Pharmaceuticals, Inc.; 2014. [Accessed 01 Mar. 2019] (online) Available from:External Link
  2. Jardiance [EMC Label]. Ingelheim am Rhein, Germany: Boehringer Ingelheim International GmbH.; 2021. [Accessed 30 Sept. 2021] (online) Available from:External Link
  3. Jardiance [Summary of Product Characteristics]. Latina, Italy: Janssen-Cilag SpA. [Accessed 30 Sept. 2021] (online) Available from:External Link
  4. Jardiance [Product Monograph].Ridgefield, USA:Boehringer Ingelheim Pharmaceuticals, Inc.; 2021. [Accessed 30 Sept. 2021] (online) Available from:External Link
  5. American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110. [Accessed 30 Sept. 2021] (online) Available from:External Link
  6. Boehringer Ingelheim. Jardiance [Empagliflozin: Patient Profile]. [Accessed 20 June 2023]. (online) Available from:External Link
  7. Empagliflozin [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2023. [Accessed 20 June 2023]. (online) Available from:External Link

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