Nebzmart-G 25mcg Smartules 2ml

Product Introduction

Tendia M Tablet SR is a medication commonly prescribed for the management of type 2 diabetes mellitus. This oral hypoglycemic agent is a combination of two active ingredients: Teneligliptin and Metformin. Each component works through different mechanisms to control blood sugar levels, offering a synergistic effect that enhances overall glucose management.

• Teneligliptin: Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. By inhibiting the DPP-4 enzyme, it increases the levels of incretin hormones, which in turn increase insulin secretion and decrease glucagon levels, leading to better glucose control.
• Metformin: Metformin belongs to the biguanide class of drugs. It reduces hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Tendia M Tablet SR is designed for sustained release (SR), meaning it releases the active ingredients slowly over time to provide a prolonged therapeutic effect and maintain steady blood glucose levels throughout the day. This formulation helps in reducing the frequency of dosing and enhances patient compliance.

Uses of Tendia M Tablet SR

Tendia M Tablet SR is primarily used in the management of type 2 diabetes mellitus. It is prescribed when diet, exercise, and monotherapy with either Teneligliptin or Metformin alone do not provide adequate glycemic control. The combination therapy of Tendia M Tablet SR is beneficial for:

• Improving Glycemic Control: By targeting multiple pathways involved in glucose regulation, Tendia M Tablet SR effectively lowers both fasting and postprandial blood glucose levels.
• Reducing HbA1c Levels: This medication helps in reducing the glycated hemoglobin (HbA1c) levels, an important marker of long-term glucose control.
• Preventing Diabetes Complications: By maintaining optimal blood glucose levels, Tendia M Tablet SR helps in reducing the risk of complications associated with diabetes, such as neuropathy, nephropathy, retinopathy, and cardiovascular diseases.

Benefits of Tendia M Tablet SR

The combination of Teneligliptin and Metformin in Tendia M Tablet SR offers several benefits:

• Enhanced Glycemic Control: The dual action of Teneligliptin and Metformin provides a comprehensive approach to managing blood sugar levels.
• Convenience: The sustained release formulation allows for once-daily dosing, improving patient adherence to the treatment regimen.
• Weight Neutrality: Unlike some other antidiabetic medications, Tendia M Tablet SR is weight-neutral, meaning it does not cause significant weight gain.
• Low Risk of Hypoglycemia: The risk of hypoglycemia (low blood sugar levels) is lower with this combination therapy compared to other treatments, making it a safer option for many patients.
• Cardiovascular Benefits: Emerging evidence suggests that DPP-4 inhibitors like Teneligliptin may have cardiovascular benefits, adding an extra layer of protection for patients with diabetes who are at higher risk of heart disease.

Side Effects of Tendia M Tablet SR

While Tendia M Tablet SR is generally well-tolerated, some patients may experience side effects. These can range from mild to moderate in severity. It is important to monitor for any adverse reactions and consult a healthcare provider if they occur. Common side effects include:

• Gastrointestinal Issues: Metformin, one of the components of Tendia M Tablet SR, is known to cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal discomfort. These symptoms are usually transient and may subside with continued use.
• Headache: Some patients may experience headaches while taking Tendia M Tablet SR.
• Upper Respiratory Tract Infections: There is a slightly increased risk of upper respiratory tract infections with the use of DPP-4 inhibitors like Teneligliptin.
• Hypoglycemia: Although the risk is lower compared to other antidiabetic agents, hypoglycemia can still occur, especially when Tendia M Tablet SR is used in combination with other glucose-lowering medications.
• Vitamin B12 Deficiency: Long-term use of Metformin has been associated with reduced absorption of vitamin B12, which can lead to deficiency over time. Monitoring and supplementation may be necessary.
• Allergic Reactions: Rarely, allergic reactions such as rash, itching, or swelling can occur. Immediate medical attention is required if any signs of a severe allergic reaction are observed.

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