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Niftran 100mg Capsule

Original price was: ₹96.76.Current price is: ₹87.08.

Prescription Required

Salt : Nitrofurantoin (100mg)

Manufacturer : Sun Pharmaceutical Industries Ltd

Packing : 10 capsules in 1 bottle

Description

Product Introduction

Niftran 100mg Capsule is a prescription medication primarily used to treat urinary tract infections (UTIs). The active ingredient in Niftran is nitrofurantoin, an antibiotic that belongs to the nitrofuran class. Nitrofurantoin is effective against a broad spectrum of Gram-positive and Gram-negative bacteria, making it a versatile treatment for bacterial infections specifically targeting the urinary tract.

Niftran 100mg Capsule is manufactured in capsule form, making it easy to swallow and ensuring precise dosage. It works by inhibiting bacterial DNA, RNA, protein, and cell wall synthesis, effectively killing the bacteria responsible for the infection. The capsule is typically orange and white, clearly marked to avoid confusion with other medications.

Uses of Niftran 100mg Capsule

The primary use of Niftran 100mg Capsule is to treat urinary tract infections. UTIs are a common medical condition, especially in women, and they occur when bacteria invade the urinary system, which includes the bladder, kidneys, ureters, and urethra. Nitrofurantoin, the active component of Niftran, is particularly effective in treating uncomplicated lower UTIs, such as cystitis (bladder infection).

In addition to treating active infections, Niftran 100mg Capsule can also be used prophylactically to prevent recurrent UTIs. This is especially useful for individuals who suffer from frequent infections. In such cases, a lower dose may be prescribed over an extended period.

Benefits of Niftran 100mg Capsule

Effective Against Resistant Strains: One of the significant advantages of Niftran 100mg Capsule is its effectiveness against bacteria that have developed resistance to other antibiotics. This makes it a valuable option in the treatment of UTIs, where antibiotic resistance is a growing concern.

Targeted Action: Nitrofurantoin concentrates in the urine, providing targeted action against bacteria in the urinary tract. This ensures a higher efficacy in treating UTIs compared to some other antibiotics that may not concentrate as effectively in the urinary system.

Rapid Symptom Relief: Patients typically experience rapid relief from UTI symptoms, such as painful urination, frequent urination, and abdominal pain, within a few days of starting treatment with Niftran.

Preventive Use: For patients prone to recurrent UTIs, Niftran 100mg Capsule can be used as a preventive measure. This reduces the frequency of infections and improves the overall quality of life.

Low Risk of Severe Side Effects: While all medications have potential side effects, Niftran 100mg Capsule is generally well-tolerated by most patients. The risk of severe side effects is relatively low compared to some other antibiotics.

Side Effects of Niftran 100mg Capsule

Like all medications, Niftran 100mg Capsule can cause side effects, although not everyone will experience them. Common side effects include:

Gastrointestinal Issues: The most frequently reported side effects are related to the gastrointestinal system. These include nausea, vomiting, loss of appetite, and diarrhea. Taking the capsule with food can help minimize these effects.

Allergic Reactions: Some patients may experience allergic reactions to nitrofurantoin. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, and trouble breathing. If any of these symptoms occur, medical attention should be sought immediately.

Pulmonary Reactions: Nitrofurantoin has been associated with pulmonary reactions, which can be acute or chronic. Acute pulmonary reactions may present as fever, chills, cough, chest pain, and difficulty breathing, usually occurring within the first week of treatment. Chronic pulmonary reactions are less common but can occur with prolonged use, presenting as cough, shortness of breath, and pulmonary fibrosis.

Liver Toxicity: Although rare, nitrofurantoin can cause liver toxicity. Symptoms include jaundice (yellowing of the skin or eyes), dark urine, severe stomach/abdominal pain, and persistent nausea/vomiting.

Peripheral Neuropathy: Long-term use of Niftran 100mg Capsule can lead to peripheral neuropathy, a condition where the nerves outside the brain and spinal cord are damaged. Symptoms include tingling, numbness, and pain in the hands and feet.

Hematological Effects: Rarely, nitrofurantoin can affect the blood, leading to conditions like hemolytic anemia (especially in patients with G6PD deficiency), leukopenia, and thrombocytopenia. Symptoms include unusual fatigue, shortness of breath, and easy bruising/bleeding.

References

  1. Petri WA Jr. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1474-75.
  2. Chambers HF, Deck DH. Miscellaneous Antimicrobial Agents; Disingectants, Antiseptics, & Sterilants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 878.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 984-86.
  4. Nitrofurantoin. North Norwich, New York: Norwich Pharmaceuticals, Inc.; 2008. [Accessed 28 Mar. 2019] (online) Available form:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  6. Nitrofurantoin monohydrate/macrocrystals [Prescribing Information]. North Norwich, NY: Norwich Pharmaceuticals, Inc.; 2008. [Accessed 06 Apr. 2023] (online) Available from: External Link

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Singhla Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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