Olparib 100mg Tablet

Product Introduction

Olparib 100mg Tablet is a targeted cancer therapy that belongs to a class of medications known as poly(ADP-ribose) polymerase (PARP) inhibitors. It is primarily used in the treatment of certain types of cancer, particularly breast and ovarian cancers that harbor specific genetic mutations. The drug functions by inhibiting the PARP enzyme, which plays a crucial role in repairing DNA damage in cells. By preventing the repair of damaged DNA in cancer cells, Olparib leads to cell death and helps to slow down or stop the progression of the tumor.

Olparib is especially indicated for patients with advanced ovarian cancer who have responded to previous chemotherapy and for those with a BRCA1 or BRCA2 mutation. The medication has shown promise in extending progression-free survival in patients with these specific genetic profiles. Olparib is available in tablet form, with each tablet containing 100mg of the active ingredient. It is typically prescribed to be taken orally, twice daily, with or without food.

Uses of Olparib 100mg Tablet

Olparib is primarily indicated for the following uses:

1. Ovarian Cancer Treatment: It is used for the maintenance treatment of adult patients with recurrent ovarian cancer who are in a complete or partial response to platinum-based chemotherapy.
2. Breast Cancer: Olparib is also approved for the treatment of patients with HER2-negative breast cancer who have a germline BRCA mutation and have previously received chemotherapy.
3. Pancreatic Cancer: In some cases, Olparib is prescribed for the treatment of pancreatic cancer in patients with BRCA mutations.
4. Prostate Cancer: The medication is used in specific instances of metastatic castration-resistant prostate cancer in patients who have a mutation in the BRCA gene.

Benefits of Olparib 100mg Tablet

The benefits of Olparib include:

• Targeted Therapy: As a PARP inhibitor, Olparib selectively targets cancer cells with defective DNA repair mechanisms, minimizing damage to healthy cells.
• Improved Survival Rates: Clinical studies have shown that Olparib can significantly prolong progression-free survival in patients with specific types of cancer.
• Convenient Administration: The oral tablet form allows for easy administration at home, improving patient compliance.
• Management of Genetic Cancer Risk: For patients with BRCA mutations, Olparib offers an effective treatment option, addressing the underlying genetic predisposition to certain cancers.

Side Effects of Olparib 100mg Tablet

While Olparib is an effective treatment, it may cause side effects in some patients. Common side effects include:

• Nausea and Vomiting: Some patients may experience gastrointestinal discomfort, including nausea and vomiting.
• Fatigue: A general sense of tiredness or weakness is commonly reported.
• Anemia: Reduced levels of red blood cells may lead to symptoms such as weakness and pale skin.
• Increased Risk of Infections: Olparib can affect bone marrow function, leading to lower white blood cell counts and increased susceptibility to infections.
• Liver Enzyme Elevation: Some patients may experience increased levels of liver enzymes, which should be monitored through regular blood tests.
• Diarrhea: Some patients may experience episodes of diarrhea.

FAQ

1. How should Olparib be taken?
   • Olparib should be taken exactly as prescribed by your healthcare provider. It is usually taken orally, twice daily, with or without food. Swallow the tablet whole with a glass of water; do not crush or chew it.
2. What should I do if I miss a dose?
   • If you miss a dose of Olparib, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.
3. Can Olparib be taken with other medications?
   • Inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions. Certain medications may affect how Olparib works.
4. What should I do if I experience severe side effects?
   • If you experience severe side effects such as difficulty breathing, severe dizziness, or symptoms of infection (fever, chills, persistent sore throat), seek immediate medical attention.
5. Is there any specific monitoring required while on Olparib?
   • Yes, your healthcare provider will likely monitor your blood counts and liver function regularly while you are on Olparib to ensure your safety and to manage any side effects.

Disclaimer

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