Pacliaqualip 30Mg Injection

Pacliaqualip 30mg Injection is a medication primarily used in the treatment of various types of cancer, including ovarian cancer, breast cancer, lung cancer, and pancreatic cancer. It belongs to a class of medications known as taxanes and works by inhibiting the growth of cancer cells.

This injection contains paclitaxel as its active ingredient, which is a potent anti-cancer agent. Paclitaxel works by interfering with the microtubule structures in cancer cells, thereby disrupting their ability to divide and grow. Pacliaqualip 30mg Injection is typically administered intravenously by a healthcare professional in a hospital or clinic setting.

USES OF Pacliaqualip 30Mg Injection

Pacliaqualip 30mg Injection is prescribed for the following conditions:

• Ovarian Cancer: Pacliaqualip is often used in combination with other chemotherapy medications for the treatment of ovarian cancer, particularly in cases where the cancer has spread beyond the ovaries.
• Breast Cancer: It is used in the treatment of advanced or metastatic breast cancer, either as a single agent or in combination with other anti-cancer drugs.
• Lung Cancer: Pacliaqualip may be prescribed for non-small cell lung cancer, either alone or in combination with other chemotherapy drugs.
• Pancreatic Cancer: It is sometimes used as a part of chemotherapy regimens for the treatment of advanced pancreatic cancer.

BENEFITS OF Pacliaqualip 30Mg Injection

• Effective Cancer Treatment: Pacliaqualip 30mg Injection is highly effective in killing cancer cells and shrinking tumors, thereby slowing down the progression of various types of cancer.
• Wide Spectrum of Activity: It is used in the treatment of several types of cancer, making it a versatile chemotherapy agent.
• Improved Survival Rates: When used as part of a comprehensive cancer treatment plan, Pacliaqualip has been shown to improve survival rates and prolong life expectancy in cancer patients.
• Palliative Care: In cases where cancer is advanced and cure is not possible, Pacliaqualip can provide relief from symptoms and improve the quality of life by reducing pain and discomfort associated with cancer.

SIDE EFFECTS OF Pacliaqualip 30Mg Injection

While Pacliaqualip 30mg Injection is an effective medication for treating cancer, it may also cause several side effects. These side effects can vary in severity from mild to severe and may include:

• Nausea and Vomiting: One of the most common side effects of Pacliaqualip is nausea and vomiting, which can usually be managed with anti-nausea medications.
• Hair Loss: Many patients experience temporary hair loss or thinning while undergoing treatment with Pacliaqualip. Hair typically regrows once treatment is completed.
• Bone Marrow Suppression: Pacliaqualip can suppress the bone marrow’s ability to produce blood cells, leading to a decrease in white blood cells, red blood cells, and platelets. This can increase the risk of infections, anemia, and bleeding.
• Peripheral Neuropathy: Some patients may experience tingling, numbness, or pain in the hands and feet, known as peripheral neuropathy. This side effect is usually reversible and may improve after discontinuing treatment.
• Allergic Reactions: In rare cases, Pacliaqualip may cause allergic reactions, which can manifest as rash, itching, difficulty breathing, or swelling of the face, lips, or tongue. Immediate medical attention is required if an allergic reaction occurs.

REFERENCES

1. KD. Tripathi. Anticancer drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page –865.

2. Maela C. Farrar; Tibb F. Jacobs. Paclitaxel.  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in May 2022] [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/books/NBK536917

3. Kyohei Kanematsu, Hironori Tsujimoto,∗ Shinsuke Nomura, Hiroyuki Horiguchi, Nozomi Ito, Kenji Yamazaki, Shuichi Hiraki, Suefumi Aosasa, Junji Yamamoto and Kazuo Hase. Weekly paclitaxel therapy for gastric cancer in patients with renal dysfunction: A case report. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in September 2016] [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021784/

4. Denise A Yardley. Taxanes in the elderly patient with metastatic breast cancer. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in September 2015] [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567240/

5. Fresenius Kabi India Pvt. Ltd. Paclitaxel. [Accessed on 7th October 2021] https://www.fresenius-kabi.com/in/products/paclitaxel

6. Dr. Reddy’s Laboratories Ltd. Mitotax Inj. 250mg. [Accessed on 7th October 2021] https://www.drreddys.com/russia-en/products/product-list/m/mitotax-inj-250-mg/

7. Intas Pharmaceuticals Ltd. CYTAX-200. [Accessed on 7th October 2021] https://www.intaspharma.com/products/

8. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in December 2019] [Accessed on 7th October 2021] https://www.medicines.org.uk/emc/files/pil.6076.pdf

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