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Prolemax 11.25mg Injection Original price was: ₹8,853.00.Current price is: ₹6,000.00.
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Prolia 60mg Injection

Original price was: ₹21,000.00.Current price is: ₹15,800.00.

Prescription Required

Cold chain

Salt : Denosumab (60mg)

Manufacturer : Dr Reddy’s Laboratories Ltd

Packing : 1.0 Solution for Injection in 1 prefilled syringe

Prepaid Only, Non-Returnable

Description

PRODUCT INTRODUCTION

Prolia 60mg Injection, also known by its generic name denosumab, is a medication used primarily in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It belongs to a class of drugs known as monoclonal antibodies and works by inhibiting the activity of cells responsible for breaking down bone tissue, thereby increasing bone mass and strength.

USES OF PROLIA 60MG INJECTION

Prolia 60mg Injection is primarily prescribed for:

  • Osteoporosis: It is used to treat osteoporosis in postmenopausal women and in men at high risk of fractures. Osteoporosis is a condition characterized by weakened bones, making them more prone to fractures and breaks. Prolia helps to strengthen bones and reduce the risk of fractures.
  • Bone Loss: It is also used to prevent bone loss in patients undergoing hormone deprivation therapy for breast or prostate cancer. Hormone therapy can accelerate bone loss, leading to conditions such as osteoporosis. Prolia helps to counteract this bone loss and maintain bone density.

BENEFITS OF PROLIA 60MG INJECTION

  • Increased Bone Density: Prolia works by increasing bone mass and strength, thereby reducing the risk of fractures associated with osteoporosis and bone loss conditions.
  • Fracture Prevention: By strengthening bones, Prolia helps to reduce the risk of fractures, particularly in postmenopausal women and men undergoing hormone deprivation therapy.
  • Convenient Administration: Prolia is administered via injection, typically once every six months, making it a convenient treatment option for patients who may have difficulty with oral medications or who require long-term therapy.
  • Effective in High-Risk Patients: Prolia has been shown to be effective in reducing fracture risk in high-risk populations, including elderly individuals and those with existing fractures or low bone density.

SIDE EFFECTS OF PROLIA 60MG INJECTION

While Prolia is generally well-tolerated, like all medications, it can cause side effects in some individuals. Common side effects may include:

  • Injection Site Reactions: Pain, redness, swelling, or itching at the injection site are common side effects of Prolia injections. These symptoms are usually mild and resolve on their own within a few days.
  • Musculoskeletal Pain: Some patients may experience muscle or joint pain, which is usually mild to moderate in severity and tends to improve with continued use of the medication.
  • Infections: Prolia may increase the risk of certain infections, including urinary tract infections and upper respiratory tract infections. Patients should be vigilant for signs of infection and seek medical attention if symptoms develop.
  • Hypocalcemia: Prolia can lower calcium levels in the blood, leading to symptoms such as muscle spasms, numbness or tingling in the fingers or toes, and confusion. Patients may need to take calcium and vitamin D supplements to prevent or treat hypocalcemia.
  • Osteonecrosis of the Jaw: In rare cases, Prolia may increase the risk of osteonecrosis of the jaw, a condition characterized by the death of bone tissue in the jaw. Patients should practice good oral hygiene and undergo dental exams before starting Prolia treatment to reduce this risk.
  • Atypical Femoral Fractures: Prolia has been associated with an increased risk of atypical fractures of the thigh bone. Patients should be monitored for signs of thigh pain or discomfort, which may indicate a possible fracture.

REFERENCES

1. KD.Tripathi. Hormones and Drugs Affecting Calcium Balance. Essentials of Medical Pharmacology. Eight Edition. 2019. Page – 371-372.

2. D A Hanley, J D Adachi, A Bell, V Brown.Denosumab: mechanism of action and clinical outcomes. [Revised on December 2012] [Accessed on 4th May 2022] https://pubmed.ncbi.nlm.nih.gov/22967310/

3. Olivier Lamy, Delphine Stoll, BérengèreAubry-Rozier, Elena Gonzalez Rodriguez.Stopping Denosumab. [Revised in February 2019] [Accessed on 4th May 2022] https://pubmed.ncbi.nlm.nih.gov/30659428/

4. Amgen Technology (Ireland) Unlimited Company. Electronic Medicines Compendium (EMC). [Revised in September 2021] [Accessed on 4th May 2022] https://www.medicines.org.uk/emc/files/pil.568.pdf

5. Denosumab. Mayoclinic. [Revised in August 2021] [Accessed on 4th May 2022] https://www.mayoclinic.org/diseases-conditions/osteoporosis/symptoms-causes/syc-20351968

6. Denosumab. Chemocare. [Accessed in 4th May2022] https://chemocare.com/chemotherapy/drug-info/denosumab.aspx

Disclaimer

Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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