Regonat 40mg Tablet

Regonat 40mg Tablet, a medication manufactured by Natco Pharma Ltd., is a potent kinase inhibitor used primarily in the treatment of gastrointestinal stromal tumors (GIST) and metastatic renal cell carcinoma (mRCC). The active ingredient in Regonat, Regorafenib, belongs to a class of medications known as multikinase inhibitors, which work by blocking certain enzymes involved in the growth and spread of cancer cells.

USES OF Regonat 40mg Tablet

Regonat 40mg Tablet finds its primary application in the management of two types of cancers:

Gastrointestinal Stromal Tumors (GIST): GIST is a rare form of cancer that originates in the gastrointestinal tract, most commonly in the stomach or small intestine. Regonat is prescribed for patients with GIST who have been previously treated with imatinib mesylate and sunitinib malate but have shown disease progression or intolerance to these treatments.

Metastatic Renal Cell Carcinoma (mRCC): mRCC is a type of kidney cancer that has spread beyond the kidneys to other parts of the body. Regonat is used as a second-line treatment for mRCC in patients who have received prior therapy with tyrosine kinase inhibitors.

BENEFITS OF Regonat 40mg Tablet

Efficacy: Clinical studies have demonstrated that Regonat 40mg Tablet can significantly prolong progression-free survival in patients with advanced GIST and mRCC compared to placebo.

Treatment Options: Regonat provides an additional treatment option for patients who have not responded to or have become resistant to other standard therapies for GIST and mRCC.

Improved Quality of Life: By slowing down the progression of cancer, Regonat can help alleviate symptoms associated with advanced GIST and mRCC, leading to an improved quality of life for patients.

Longer Survival: In some cases, Regonat may contribute to extending overall survival rates in patients with advanced GIST and mRCC.

SIDE EFFECTS OF Regonat 40mg Tablet

While Regonat 40mg Tablet can be an effective treatment for certain types of cancer, it is essential to be aware of potential side effects that may occur during the course of therapy. Common side effects of Regonat include:

Fatigue: Many patients experience fatigue or weakness while taking Regonat, which can impact daily activities and quality of life.

Hypertension: Regonat can cause an increase in blood pressure, which may require monitoring and management with antihypertensive medications.

Hand-Foot Skin Reaction: Some individuals may develop redness, swelling, or pain on the palms of the hands or soles of the feet, known as hand-foot skin reaction.

Diarrhea: Diarrhea is a common side effect of Regonat treatment, which can lead to dehydration and electrolyte imbalances if not adequately managed.

Decreased Appetite: Many patients may experience a loss of appetite or weight loss while taking Regonat, which can contribute to nutritional deficiencies.

Liver Toxicity: Regonat can affect liver function, leading to elevated liver enzymes or liver damage in some cases.

Bleeding: In rare instances, Regonat may increase the risk of bleeding or bruising due to its effects on blood clotting.