Ziten-M 500mg/20mg Tablet ER

Product Introduction

Ziten-M 500mg/20mg Tablet ER is an extended-release medication that combines two active ingredients: Teneligliptin (20mg) and Metformin (500mg). This combination therapy is primarily used in the management of type 2 diabetes mellitus, a condition characterized by high blood sugar levels due to the body’s inability to use insulin effectively. Ziten-M is part of the class of medications known as antidiabetic agents and is particularly beneficial for patients who do not achieve adequate glycemic control with metformin alone or as a part of a combination therapy.

The extended-release formulation allows for a gradual release of the medication, ensuring a consistent therapeutic effect over an extended period. This helps in maintaining stable blood glucose levels throughout the day, reducing the risk of both hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).

Uses of Ziten-M 500mg/20mg Tablet ER

Ziten-M 500mg/20mg Tablet ER is primarily used for:

• Management of Type 2 Diabetes Mellitus: This medication is prescribed for adults with type 2 diabetes mellitus, particularly those who have not achieved sufficient blood sugar control through diet, exercise, or metformin monotherapy. The combination of Teneligliptin and Metformin works synergistically to improve glycemic control.
• Prevention of Complications: By effectively controlling blood sugar levels, Ziten-M helps prevent long-term complications associated with diabetes, such as cardiovascular diseases, neuropathy, nephropathy, and retinopathy.
• Improvement of Insulin Sensitivity: Metformin, one of the active ingredients, enhances insulin sensitivity, allowing the body to utilize insulin more effectively. This is particularly important for patients with insulin resistance, a common issue in type 2 diabetes.

Benefits of Ziten-M 500mg/20mg Tablet ER

• Dual Mechanism of Action: The combination of Teneligliptin and Metformin offers a dual mechanism of action. Teneligliptin is a DPP-4 inhibitor that works by increasing the levels of incretin hormones, which help regulate blood sugar levels by increasing insulin release and decreasing glucagon production. Metformin, on the other hand, decreases glucose production in the liver and improves insulin sensitivity. This dual approach enhances glycemic control more effectively than either drug alone.
• Extended-Release Formulation: The extended-release formulation of Ziten-M ensures a slow and steady release of the medication, providing consistent blood sugar control throughout the day. This reduces the frequency of dosing and enhances patient compliance.
• Reduced Risk of Hypoglycemia: Unlike some other antidiabetic medications, Ziten-M has a lower risk of causing hypoglycemia (low blood sugar levels). This is because Teneligliptin increases insulin secretion in response to meals, but does not promote insulin release when blood sugar levels are normal.
• Weight Neutral: Teneligliptin is considered weight-neutral, meaning it does not cause significant weight gain, a common concern with many antidiabetic medications. This is particularly beneficial for patients with type 2 diabetes who may already be struggling with weight management.

Side Effects of Ziten-M 500mg/20mg Tablet ER

While Ziten-M 500mg/20mg Tablet ER is generally well-tolerated, some patients may experience side effects. These can vary in severity and may include:

• Gastrointestinal Issues: Common side effects associated with Metformin include nausea, vomiting, diarrhea, abdominal discomfort, and a metallic taste in the mouth. These symptoms are usually mild and tend to improve over time as the body adjusts to the medication.
• Hypoglycemia: Although Ziten-M has a lower risk of causing hypoglycemia compared to other antidiabetic agents, it can still occur, particularly if the patient skips meals, exercises excessively, or consumes alcohol. Symptoms of hypoglycemia include dizziness, sweating, tremors, and confusion.
• Lactic Acidosis: A rare but serious side effect associated with Metformin is lactic acidosis, a condition characterized by the buildup of lactic acid in the blood. This can occur in patients with kidney or liver impairment, or those with other conditions that predispose them to this risk. Symptoms of lactic acidosis include rapid breathing, muscle pain, abdominal pain, and fatigue. Immediate medical attention is required if these symptoms occur.
• Allergic Reactions: Some patients may experience allergic reactions to Ziten-M, including rash, itching, swelling, dizziness, and difficulty breathing. In such cases, the medication should be discontinued, and medical advice should be sought.

 FAQ

Q1: How should I take Ziten-M 500mg/20mg Tablet ER?
A1: Ziten-M should be taken as prescribed by your healthcare provider. It is usually taken once daily with food to reduce the risk of gastrointestinal side effects. Swallow the tablet whole with a glass of water without crushing or chewing it.

Q2: Can I stop taking Ziten-M if my blood sugar levels are normal?
A2: No, you should not stop taking Ziten-M without consulting your healthcare provider. Stopping the medication abruptly can cause your blood sugar levels to rise. Your doctor will guide you on how to adjust or discontinue the medication if necessary.

Q3: What should I do if I miss a dose?
A3: If you miss a dose of Ziten-M, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take the next one as scheduled. Do not double the dose to make up for the missed one.

Q4: Can I drink alcohol while taking Ziten-M?
A4: It is advisable to limit alcohol consumption while taking Ziten-M, as alcohol can increase the risk of lactic acidosis and hypoglycemia. Discuss your alcohol consumption with your doctor.

Q5: Are there any dietary restrictions while taking Ziten-M?
A5: While taking Ziten-M, it is important to follow a balanced diet and avoid high-sugar foods that can spike your blood sugar levels. Your healthcare provider may provide specific dietary recommendations based on your condition.

Q6: Can Ziten-M be used in pregnancy or breastfeeding?
A6: Ziten-M is generally not recommended during pregnancy or breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, discuss alternative treatment options with your healthcare provider.

Q7: How does Ziten-M interact with other medications?
A7: Ziten-M may interact with other medications, including insulin, other antidiabetic drugs, and medications that affect kidney function. Inform your healthcare provider of all medications you are taking to avoid potential interactions.

Disclaimer

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