

Adsunib 50mg Capsule
₹7,400.00 Original price was: ₹7,400.00.₹5,250.00Current price is: ₹5,250.00.
Prescription Required
Salt : Sunitinib
Manufacturer : Adley Formulations
Packing : 28 Capsule In A Bottle
PRODUCT INTRODUCTION
Adsunib 50mg Capsule is a potent medication formulated for the treatment of specific types of cancer, primarily kidney cancer (renal cell carcinoma) and gastrointestinal stromal tumors (GIST). The active ingredient in Adsunib is Sunitinib, which belongs to a class of medications known as tyrosine kinase inhibitors (TKIs). Sunitinib works by blocking the action of abnormal proteins that signal cancer cells to multiply. This inhibition helps to halt the growth and spread of cancer cells.
Adsunib 50mg Capsule is a pivotal advancement in oncology therapeutics, offering a targeted approach to cancer treatment. It is typically prescribed when other forms of treatment, such as surgery or radiation, are not viable options or have failed to produce desired results. The capsule is usually taken once a day, and the dosage and duration of the treatment depend on the type and severity of cancer, as well as the patient’s overall health and response to the medication.
USES OF ADSUNIB 50MG CAPSULE
Adsunib 50mg Capsule is primarily indicated for:
- Renal Cell Carcinoma (RCC): RCC is the most common type of kidney cancer, originating in the lining of the small tubes in the kidney. Adsunib is used as a first-line treatment or when other therapies have failed.
- Gastrointestinal Stromal Tumors (GIST): GISTs are tumors that occur in the digestive tract, most commonly in the stomach or small intestine. Adsunib is prescribed for patients with GIST who cannot undergo surgery or whose disease has progressed despite treatment with other medications.
- Pancreatic Neuroendocrine Tumors (pNET): These are rare types of cancer that form in the hormone-producing cells of the pancreas. Adsunib is used for patients with advanced pNET when the disease has progressed or cannot be surgically removed.
BENEFITS OF ADSUNIB 50MG CAPSULE
The benefits of Adsunib 50mg Capsule are significant in the context of advanced cancer treatment. These include:
- Targeted Therapy: Adsunib provides a targeted approach, specifically inhibiting the tyrosine kinase enzymes that are involved in tumor growth and angiogenesis (formation of new blood vessels to supply the tumor).
- Improved Survival Rates: Clinical studies have shown that Adsunib can extend the progression-free survival and overall survival rates in patients with RCC and GIST, providing a substantial improvement in quality of life and disease management.
- Management of Symptoms: By controlling the growth and spread of tumors, Adsunib helps in managing the symptoms associated with advanced cancers, such as pain, fatigue, and weight loss, thereby improving the patient’s quality of life.
- Oral Administration: Adsunib is taken orally, which is convenient compared to intravenous chemotherapy. This allows for outpatient treatment and reduces the need for hospital visits.
SIDE EFFECTS OF ADSUNIB 50MG CAPSULE
While Adsunib 50mg Capsule offers considerable benefits, it is also associated with several side effects. Patients should be closely monitored, and side effects should be managed under the guidance of a healthcare professional. Common side effects include:
- Gastrointestinal Issues: Nausea, vomiting, diarrhea, and loss of appetite are frequent. These symptoms can usually be managed with supportive care and medications to prevent dehydration and maintain nutritional status.
- Fatigue: A common side effect, fatigue can be profound and impact daily activities. Patients are advised to balance rest with mild physical activity to maintain energy levels.
- Hypertension: Elevated blood pressure is a significant concern. Regular monitoring and appropriate antihypertensive medications may be required.
- Hand-Foot Syndrome: This condition causes redness, swelling, and pain on the palms of the hands and soles of the feet. Dose adjustments and symptomatic treatments like emollients can help manage these symptoms.
- Hematological Effects: Adsunib can cause myelosuppression, leading to decreased levels of red blood cells, white blood cells, and platelets. Regular blood tests are necessary to monitor these parameters, and treatment modifications may be required based on the results.
- Liver Function: Elevated liver enzymes can occur, indicating liver inflammation or damage. Liver function tests should be conducted periodically, and any significant changes should prompt a reassessment of the treatment regimen.
- Cardiovascular Effects: Rare but serious side effects include heart failure and myocardial infarction. Patients with pre-existing cardiovascular conditions require careful monitoring.
- Other Effects: Other side effects may include skin discoloration, hair color changes, and thyroid dysfunction. Patients should report any unusual symptoms to their healthcare provider promptly.
References
- Pfizer, U.S Drug and food safety administration (FDA), [Revised on Dec 2018], [Accessed on 5th April 2023],
https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021938s035lbl.pdf - Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
- Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo, Tyrosine Kinase Inhibitors, [Revised on 21st Jan 2021] [Accessed on 5th April 2023],
https://www.ncbi.nlm.nih.gov/books/NBK563322/ - Pfizer, Electronic Medicines Compendium (EMC) [Revised on Mar 2021] [Accessed on 5th April 2023],  https://www.medicines.org.uk/emc/files/pil.7966.pdf
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936
Disclaimer
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