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Afinitor 5mg Tablet

Original price was: ₹9,797.00.Current price is: ₹7,837.60.

Prescription Required

Salt : Everolimus

Manufacturer : Novartis India Ltd

Packing : 10 Tablet In A Strip

Description

PRODUCT INTRODUCTION

Afinitor 5mg Tablet, a brand name for the drug everolimus, stands as a beacon of hope in the realm of oncology and immunosuppressive therapy. It belongs to the class of medications known as mTOR inhibitors, meticulously engineered to disrupt cancer cell growth and prevent rejection in organ transplant recipients. This orally administered tablet encapsulates the promise of advanced pharmaceutical science in combating formidable diseases.

USES OF AFINITOR 5MG TABLET

1. Cancer Treatment: Afinitor 5mg Tablet is primarily employed in the treatment of various types of cancer. It acts as a potent inhibitor of the mTOR pathway, crucial for cellular proliferation, angiogenesis, and survival. In patients diagnosed with advanced kidney cancer, Afinitor serves as a beacon of hope, offering a therapeutic avenue when other treatment modalities fail. Additionally, for individuals grappling with hormone receptor-positive, HER2-negative breast cancer, Afinitor, in combination with exemestane, presents a formidable duo, extending progression-free survival and enhancing overall outcomes.

2. Organ Transplantation: In the realm of organ transplantation, Afinitor 5mg Tablet plays a pivotal role in preventing organ rejection. When administered in conjunction with other immunosuppressive agents, it helps thwart the immune system’s assault on the transplanted organ, ensuring long-term graft survival. This property makes Afinitor an indispensable component of the post-transplant pharmacological arsenal, fostering the dream of a life unshackled from the clutches of organ rejection.

BENEFITS OF AFINITOR 5MG TABLET

1. Prolonged Progression-Free Survival: For cancer patients, particularly those with advanced renal cell carcinoma or hormone receptor-positive, HER2-negative breast cancer, Afinitor 5mg Tablet bestows the invaluable gift of time. By halting the unbridled proliferation of cancer cells, Afinitor extends progression-free survival, providing patients with precious moments of respite from the relentless onslaught of their disease. This extended period of disease control not only enhances quality of life but also affords patients the opportunity to explore alternative treatment options or participate in clinical trials, ushering in rays of hope amidst the gloom.

2. Preservation of Organ Function: In the context of organ transplantation, the benefits of Afinitor 5mg Tablet are manifold. By delicately modulating the immune response, Afinitor aids in preserving the function of transplanted organs, ensuring their longevity and functionality. This translates into enhanced quality of life for transplant recipients, as they navigate the intricate labyrinth of post-transplant care with renewed optimism and vigor. Moreover, the reduced incidence of acute rejection episodes minimizes the need for high-dose immunosuppressive therapy, mitigating the risk of adverse effects and complications.

SIDE EFFECTS OF AFINITOR 5MG TABLET

While Afinitor 5mg Tablet heralds a new dawn in the realm of cancer therapy and organ transplantation, its journey is not devoid of challenges. Like all medications, Afinitor is accompanied by a spectrum of potential side effects, ranging from mild to severe, necessitating vigilant monitoring and proactive management.

1. Common Side Effects: Patients undergoing treatment with Afinitor may experience a myriad of common side effects, including but not limited to fatigue, nausea, diarrhea, and stomatitis. These adverse effects, though often transient and manageable, may significantly impact patients’ quality of life, necessitating dose modifications or symptomatic management.

2. Metabolic Disturbances: Afinitor 5mg Tablet is also associated with metabolic disturbances, including hyperglycemia, hyperlipidemia, and electrolyte imbalances. These perturbations, though reversible in most cases, require close monitoring to prevent the development of serious complications such as diabetic ketoacidosis or cardiac arrhythmias.

3. Immunological Effects: Given its immunosuppressive properties, Afinitor may predispose patients to an increased risk of infections, ranging from benign upper respiratory tract infections to life-threatening opportunistic pathogens. Vigilant surveillance for signs of infection and prompt intervention are paramount in mitigating this risk and ensuring favorable outcomes.

4. Hematological Abnormalities: Afinitor therapy has been associated with hematological abnormalities, including anemia, thrombocytopenia, and leukopenia. These alterations in blood counts necessitate regular monitoring and, if deemed necessary, dose adjustments to prevent the development of complications such as bleeding or infections.

References

  1. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on June 2022] [ Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.6658.pdf
  2. Jan Hasskarl; Everolimus; Recent Results in Cancer Research; Published on 2018; Accessed on 18/03/2023; https://pubmed.ncbi.nlm.nih.gov/30069763/
  3. Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [ Revised on July 2012] [ Accessed on 18th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted therapy: tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1743.
  5. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878 – 882.

Disclaimer

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Shipping & Delivery

Shipping Policy

We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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