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Aromasin 25mg Tablet

Original price was: ₹5,873.47.Current price is: ₹5,286.12.

 Prescription Required

Salt : Exemestane (25mg)

Manufacturer : Pfizer Ltd

Packing : 15 tablets in 1 strip

Description

PRODUCT INTRODUCTION

Aromasin 25mg Tablet is a pharmaceutical formulation designed to alleviate hormone receptor-positive breast cancer, particularly in postmenopausal women. Each tablet contains 25mg of the active ingredient, exemestane. This medication belongs to a class of drugs known as aromatase inhibitors. Aromatase inhibitors work by blocking the enzyme aromatase, which is responsible for converting androgens into estrogen. By inhibiting estrogen production, Aromasin helps to deprive estrogen-dependent cancer cells of their growth stimulus.

USES OF Aromasin 25mg Tablet

Aromasin 25mg Tablet is primarily prescribed for the treatment of hormone receptor-positive breast cancer in postmenopausal women. This type of breast cancer relies on estrogen to fuel its growth. By inhibiting estrogen synthesis, Aromasin impedes the progression of the disease. It is commonly used in the adjuvant treatment of early-stage breast cancer following surgery and radiation therapy to reduce the risk of cancer recurrence. Additionally, Aromasin may be prescribed for advanced breast cancer that has spread to other parts of the body, helping to slow down disease progression.

BENEFITS OF Aromasin 25mg Tablet

a. Effective in Breast Cancer Treatment: Clinical studies have demonstrated that Aromasin is highly effective in reducing the risk of breast cancer recurrence in postmenopausal women. It significantly prolongs disease-free survival and improves overall survival rates when used as adjuvant therapy.

b. Minimal Estrogen Suppression: Unlike other hormonal therapies, Aromasin specifically targets the aromatase enzyme, resulting in selective estrogen suppression. This targeted approach minimizes systemic estrogen depletion and reduces the risk of adverse effects associated with estrogen deficiency.

c. Well-Tolerated: Aromasin is generally well-tolerated by most patients, with few experiencing severe side effects. Its favorable safety profile makes it a preferred choice for long-term adjuvant therapy in breast cancer management.

d. Convenient Dosage Form: Aromasin is available in a convenient oral tablet form, allowing for easy administration and improved patient compliance.

e. Potential for Disease Control: In advanced breast cancer, Aromasin has demonstrated efficacy in controlling disease progression and improving quality of life. It offers a viable treatment option for patients who have failed to respond to other hormonal therapies.

SIDE EFFECTS OF Aromasin 25mg Tablet

a. Menopausal Symptoms: Since Aromasin reduces estrogen levels, it can induce or exacerbate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. These symptoms are usually manageable with supportive care and may improve over time.

b. Musculoskeletal Effects: Some patients may experience musculoskeletal symptoms such as joint pain, stiffness, and bone fractures while taking Aromasin. Regular exercise, calcium supplementation, and bisphosphonate therapy may help alleviate these symptoms and reduce the risk of bone loss.

c. Fatigue: Fatigue is a common side effect of Aromasin treatment, which can impact daily functioning and quality of life. Adequate rest, balanced nutrition, and regular exercise can help manage fatigue and improve energy levels.

d. Mood Changes: Aromasin may cause mood changes, including depression and anxiety, in some individuals. Patients experiencing significant mood disturbances should seek medical attention for appropriate management.

e. Cardiovascular Effects: Long-term use of Aromasin may be associated with an increased risk of cardiovascular events such as heart attacks and strokes. Patients with pre-existing cardiovascular conditions should be closely monitored while taking this medication.

References

  1. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1762-63.
  2. Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 527-28.
  4. Drugs.com. Exemestane. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Exemestane. New York, New York: Pfizer; 1999 [revised May 2014]. [Accessed 03 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link
  7. Exemestane [Prescribing Information]. New York, NY: Pharmacia & Upjohn Co; 2018. [Accessed 20 Feb. 2024] (online) Available from: External Link

Disclaimer

Singhla Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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