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Arpimune ME 25mg Capsule
Arpimune ME 25mg Capsule Original price was: ₹124.10.Current price is: ₹111.69.

Arpimune ME 50mg Capsule

Original price was: ₹214.40.Current price is: ₹192.96.

 Prescription Required

Salt : Ciclosporin (50mg)

Manufacturer : RPG Life Sciences Ltd

Packing : 5 soft gelatin capsules in 1 strip

Description

PRODUCT INTRODUCTION

Arpimune ME 50mg Capsule is a specialized medication primarily used in the field of transplantation medicine and autoimmune disorders. The active ingredient in Arpimune ME is Cyclosporine, a potent immunosuppressive agent that plays a crucial role in preventing organ rejection in transplant patients and managing symptoms in certain autoimmune conditions. Cyclosporine, the cornerstone of Arpimune ME, operates by selectively suppressing certain pathways in the immune system that could otherwise lead to organ rejection or exacerbate autoimmune symptoms.

Manufactured as a microemulsion formulation, Arpimune ME 50mg ensures enhanced absorption and bioavailability of cyclosporine, leading to more predictable pharmacokinetic profiles. This formulation not only enhances the effectiveness of the drug but also contributes to the consistency in achieving therapeutic drug levels in the blood, a critical aspect in the management of transplant recipients and patients with autoimmune diseases.

USES OF Arpimune ME 50mg Capsule

Arpimune ME 50mg is extensively used in several critical health scenarios, including:

  • Organ Transplantation: It is most commonly prescribed to prevent organ rejection in patients who have undergone kidney, liver, or heart transplants. By suppressing the immune response, Arpimune ME helps the body accept the new organ as its own.
  • Autoimmune Disorders: Conditions such as rheumatoid arthritis, psoriasis, and atopic dermatitis can be effectively managed with this medication. It reduces the activity of the immune system, thereby decreasing inflammation and the severity of the disease.
  • Nephrotic Syndrome: Particularly in cases not responsive to typical steroid treatments, Arpimune ME can be utilized to treat this kidney disorder, reducing proteinuria and preserving kidney function.

BENEFITS OF Arpimune ME 50mg Capsule

The benefits of Arpimune ME 50mg Capsule are profound in the domains of its application:

  • Improved Graft Survival: The primary benefit in transplant medicine is the increase in graft survival rates, which directly translates to prolonged life expectancy and quality of life for transplant patients.
  • Reduction in Autoimmune Flares: For autoimmune patients, Arpimune ME helps in reducing the frequency and severity of disease flares, which enhances their day-to-day functioning and overall health.
  • Enhanced Drug Absorption: The microemulsion formulation of Arpimune ME promotes better absorption and consistent plasma levels, making it easier to manage and adjust doses with precision, thereby optimizing therapeutic outcomes and reducing the risk of toxicity.

SIDE EFFECTS OF Arpimune ME 50mg Capsule

While Arpimune ME 50mg Capsule provides significant medical benefits, it is not devoid of side effects. Some of the more common adverse effects associated with its use include:

  • Renal Dysfunction: Since cyclosporine can be nephrotoxic, its use can lead to an increase in creatinine and urea levels, which may necessitate regular monitoring of kidney function.
  • Hypertension: An increase in blood pressure is a frequently observed side effect, requiring management through lifestyle changes or medication.
  • Gastrointestinal Issues: Symptoms such as nausea, vomiting, and diarrhea are common, especially in the initial stages of treatment.
  • Increased Risk of Infections: As an immunosuppressant, Arpimune ME reduces the body’s ability to fight infections, making patients more susceptible to viruses, bacteria, and other pathogens.
  • Metabolic Disturbances: Patients may experience disturbances in lipid and glucose metabolism, leading to hyperlipidemia or hyperglycemia.
  • Cosmetic Changes: Changes such as increased hair growth or gum hyperplasia can also occur.

References

  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1821.
  2. Wallace JL, Sharkey KA. Pharmacotherapy of Inflammatory Bowel Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1358-59.
  3. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 630-31.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 340-42.
  5. Ciclosporine. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1983 [revised 24 Jul. 2015]. [A cessed 25 Jan. 2019].(online) Available from:External Link
  6. Cyclosporine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation. [Accessed 06 Apr. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link
  8. Cyclosporine [Product Monograph]. Quebec, Canada: Novartis Pharmaceuticals Canada Inc.; 2023. [Accessed 16 Jun. 2023] (online) Available from:External Link

Disclaimer

Singhla Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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Shipping & Delivery

Shipping Policy

We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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