Cardace H 5 Tablet

Product Introduction

Cardace H 5 Tablet is a prescription medication used primarily to manage hypertension (high blood pressure) and reduce the risk of cardiovascular events such as heart attacks and strokes. Manufactured by Sanofi, Cardace H 5 is a combination drug that contains two active ingredients: Ramipril (5 mg) and Hydrochlorothiazide (12.5 mg). Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, and Hydrochlorothiazide is a thiazide diuretic. This combination works synergistically to control blood pressure more effectively than either component alone.

Ramipril functions by inhibiting the enzyme ACE, which is responsible for converting angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor that narrows blood vessels, leading to increased blood pressure. By blocking this conversion, Ramipril allows blood vessels to relax and widen, reducing blood pressure. Hydrochlorothiazide, on the other hand, helps in lowering blood pressure by removing excess fluid from the body through the kidneys. It increases the excretion of sodium and water, which reduces blood volume and consequently lowers blood pressure.

Uses of Cardace H 5 Tablet

Cardace H 5 Tablet is primarily indicated for:

• Hypertension: The main use of Cardace H 5 Tablet is to treat high blood pressure. Effective management of hypertension helps in preventing complications such as heart attacks, strokes, and kidney problems.
• Congestive Heart Failure: Cardace H 5 is sometimes prescribed for patients with heart failure to improve survival and reduce the risk of hospitalization.
• Prevention of Cardiovascular Events: For patients at high risk of cardiovascular events, particularly those with a history of coronary artery disease, stroke, or diabetes, Cardace H 5 Tablet can help in reducing the likelihood of these events.

Benefits of Cardace H 5 Tablet

• Effective Blood Pressure Control: The combination of Ramipril and Hydrochlorothiazide in Cardace H 5 Tablet ensures a more comprehensive approach to lowering blood pressure compared to monotherapy. This dual mechanism targets different pathways involved in blood pressure regulation, leading to better control.
• Reduction in Cardiovascular Risks: By effectively managing hypertension, Cardace H 5 Tablet reduces the risk of cardiovascular events such as heart attacks and strokes, which are major causes of morbidity and mortality globally.
• Management of Fluid Retention: Hydrochlorothiazide’s diuretic effect helps in managing fluid retention, which is beneficial for patients with conditions like heart failure where fluid overload is a concern.
• Improved Kidney Function: Proper control of blood pressure with Cardace H 5 Tablet can slow down the progression of kidney disease in hypertensive patients, particularly those with diabetes.
• Once-Daily Dosing: Cardace H 5 Tablet is typically taken once daily, which improves patient compliance compared to medications that require multiple doses throughout the day.

Side Effects of Cardace H 5 Tablet

Like all medications, Cardace H 5 Tablet can cause side effects, though not everyone will experience them. Some common and less common side effects include:

• Common Side Effects:
  • Dizziness and Lightheadedness: These may occur as the body adjusts to the medication, especially after the first dose or when the dosage is increased.
  • Cough: A persistent dry cough is a known side effect of ACE inhibitors like Ramipril.
  • Fatigue: Some patients may feel unusually tired or weak.
  • Headache: Headaches can occur but are generally mild.
• Less Common Side Effects:
  • Electrolyte Imbalance: Hydrochlorothiazide can lead to low levels of potassium, sodium, and magnesium in the blood, causing symptoms like muscle weakness, confusion, and irregular heartbeats.
  • Hypotension: Excessive lowering of blood pressure can lead to symptoms of low blood pressure, such as fainting and blurred vision.
  • Renal Impairment: Although rare, ACE inhibitors can affect kidney function, particularly in patients with pre-existing kidney conditions.
  • Hyperkalemia: Ramipril can increase potassium levels in the blood, leading to hyperkalemia, which can be dangerous if severe.
  • Allergic Reactions: Some patients may experience allergic reactions, which can range from mild rashes to severe conditions like angioedema, characterized by swelling of the deeper layers of the skin, particularly around the eyes and lips.