

Endace 160mg Tablet
₹1,200.00 Original price was: ₹1,200.00.₹900.00Current price is: ₹900.00.
Prescription Required
Salt : Megestrol
Manufacturer : Samarth Life Sciences Pvt Ltd
Packing : 10 Tablet In A Strip
Product Introduction
Endace 160mg Tablet is a medication primarily used in the treatment of certain types of cancer and other medical conditions requiring hormonal therapy. The active ingredient in Endace is megestrol acetate, a synthetic derivative of the naturally occurring hormone progesterone. Megestrol acetate exhibits antineoplastic properties, meaning it can inhibit the growth and spread of tumors, making it particularly effective in managing breast cancer and endometrial cancer. Additionally, Endace is utilized for its appetite-stimulating effects in patients suffering from significant weight loss due to chronic illnesses like AIDS.
Manufactured by various pharmaceutical companies, Endace 160mg Tablet is available in oral form, making it convenient for outpatient treatment. The tablet form ensures controlled and consistent dosing, which is critical in managing cancer and related conditions effectively. The medication must be prescribed by a healthcare professional, and its use is closely monitored to manage any potential side effects and to adjust dosages as necessary.
Uses of Endace 160mg Tablet
Endace 160mg Tablet is primarily indicated for the treatment of:
- Breast Cancer: It is used as a palliative treatment for metastatic breast cancer. Megestrol acetate helps in reducing the size and spread of tumors by interfering with hormone signals that promote cancer cell growth.
- Endometrial Cancer: It is also effective in managing advanced endometrial cancer. The hormone-modulating effects of megestrol acetate help in slowing down the progression of the disease.
- Cachexia (Weight Loss) and Anorexia: Endace is widely used in patients experiencing severe weight loss and appetite loss due to chronic conditions like AIDS or cancer. The appetite-stimulating properties of megestrol acetate help improve nutritional intake and body weight.
Benefits of Endace 160mg Tablet
Endace 160mg Tablet offers several benefits, particularly for patients with cancer and those experiencing significant weight loss:
- Tumor Reduction: By mimicking the effects of progesterone, megestrol acetate can slow or stop the growth of certain types of cancer cells, particularly in breast and endometrial cancer. This contributes to better disease management and can improve survival rates in some patients.
- Appetite Stimulation: One of the most significant benefits of Endace is its ability to stimulate appetite and promote weight gain. This is particularly beneficial for patients with cachexia or anorexia associated with chronic illnesses like AIDS or cancer. Improved nutritional status can enhance overall health and quality of life.
- Palliative Care: For patients with advanced cancer, Endace can be part of a palliative care regimen, providing symptomatic relief and improving the quality of life. It can help manage symptoms such as loss of appetite and significant weight loss.
- Convenient Administration: As an oral tablet, Endace is easy to administer, allowing for outpatient treatment and reducing the need for hospitalization. This convenience can significantly improve patient compliance and overall treatment outcomes.
Side Effects of Endace 160mg Tablet
While Endace 160mg Tablet is beneficial, it also comes with potential side effects. These side effects can range from mild to severe and vary from patient to patient. Common side effects include:
- Weight Gain: While this is often a desired effect for patients suffering from cachexia, it can be excessive and lead to other complications such as fluid retention and edema.
- Mood Changes: Patients may experience mood swings, anxiety, or depression. It is essential to monitor any psychological changes and consult healthcare professionals as needed.
- Gastrointestinal Issues: Nausea, vomiting, and diarrhea are common side effects. These symptoms can usually be managed with supportive care, but severe cases may require medical intervention.
- Cardiovascular Effects: Some patients might experience hypertension, thromboembolic events (like deep vein thrombosis or pulmonary embolism), or heart failure. These serious side effects necessitate immediate medical attention.
- Endocrine Effects: Prolonged use of megestrol acetate can lead to adrenal suppression, Cushing’s syndrome, or hyperglycemia, particularly in patients with a predisposition to diabetes.
- General Discomfort: Other side effects may include fatigue, weakness, dizziness, and headaches, which can impact daily activities and overall quality of life.
References
- Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
- alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
- Bines et al., Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
- G.G. Dark, A.R. Abdul Razak, Oncology, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.
Disclaimer
Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.
Shipping Policy
We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.
Delivery
The delivery times are subject to location, distance, and our logistics partners. We are not liable for any delays in delivery by the courier company/postal authorities but will help you track down a package through our partner courier services.
Your purchases may reach you from various locations in more than one package. But rest assured, you will be charged one delivery fee for the entire order. As soon as your package ships, we will email you your package tracking information.
We are bound in coverage by their reach even though we use some of India’s largest logistics companies for shipping. In case your address is in a location not served by them we would contact you to find an alternative solution to make your products reach you.
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