Xolimus 10mg Tablet
Xolimus 10mg Tablet Original price was: ₹14,999.00.Current price is: ₹8,000.00.
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Evermil 10mg Tablet
Evermil 10mg Tablet Original price was: ₹7,450.00.Current price is: ₹5,960.00.

Evergraf 0.5mg Tablet

Original price was: ₹1,570.96.Current price is: ₹1,256.76.

Prescription Required

Salt : Everolimus

Manufacturer : Mankind Pharmaceuticals Limited

Packing : 10 Tablet In A Strip

Description

PRODUCT INTRODUCTION

Evergraf 0.5mg Tablet is an immunosuppressive medication primarily used in the management of organ transplant patients. Its active ingredient is Everolimus, a derivative of the drug sirolimus. Everolimus belongs to the class of drugs known as mTOR (mammalian target of rapamycin) inhibitors, which play a crucial role in regulating cell growth, proliferation, and survival. By inhibiting the mTOR pathway, Evergraf reduces the activity of the immune system, thereby helping to prevent the body from rejecting a transplanted organ.

Evergraf 0.5mg Tablet is manufactured with precision to ensure that each dose delivers the exact amount of medication needed to achieve therapeutic effects while minimizing potential side effects. It is available in the form of tablets, making it easy to administer and convenient for patients to include in their daily regimen. The medication should be taken exactly as prescribed by a healthcare provider, who will determine the appropriate dosage and duration of treatment based on the patient’s specific medical condition and response to therapy.

USES OF EVERGRAF 0.5MG TABLET

The primary use of Evergraf 0.5mg Tablet is in the prevention of organ rejection in patients who have undergone a kidney or liver transplant. Organ rejection occurs when the recipient’s immune system recognizes the transplanted organ as foreign and attempts to attack it. By suppressing the immune system, Evergraf helps ensure the transplanted organ is accepted and functions properly within the recipient’s body.

In addition to its primary use in transplant patients, Evergraf is also being explored for its potential benefits in treating certain cancers, such as advanced renal cell carcinoma and subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis. However, these applications are typically under the guidance of specialized medical professionals and within the context of clinical trials or specific treatment protocols.

BENEFITS OF EVERGRAF 0.5MG TABLET

The key benefit of Evergraf 0.5mg Tablet lies in its ability to significantly reduce the risk of organ rejection following a kidney or liver transplant. This contributes to the long-term success of the transplant, enhancing the recipient’s quality of life and overall health outcomes. By effectively managing the immune response, Evergraf allows the transplanted organ to function optimally, which is vital for the patient’s recovery and ongoing health.

Other potential benefits of Evergraf include its use in certain oncological conditions where it can help inhibit the growth and proliferation of cancer cells. Its role in such treatments is still under investigation, but preliminary results suggest that it could offer a valuable option for patients with specific types of cancer, particularly when other treatments have failed or are unsuitable.

SIDE EFFECTS OF EVERGRAF 0.5MG TABLET

Like all medications, Evergraf 0.5mg Tablet can cause side effects, although not everyone experiences them. The severity and type of side effects can vary based on the individual patient’s overall health, dosage, and other medications they may be taking.

Common side effects include:

  • Infections: Because Evergraf suppresses the immune system, it can increase the risk of infections, which can range from mild to severe.
  • Mouth Ulcers: Some patients may experience painful sores or ulcers in the mouth.
  • Nausea and Vomiting: Gastrointestinal disturbances such as nausea, vomiting, and diarrhea can occur.
  • Fatigue: Feeling unusually tired or weak is a common side effect.
  • Swelling: Patients might experience swelling in the extremities or other parts of the body.
  • Elevated Blood Lipids: Increases in cholesterol and triglyceride levels may occur, necessitating regular monitoring and management.
  • Renal Impairment: Kidney function can be affected, especially when used in conjunction with other nephrotoxic drugs.
  • Hyperglycemia: Elevated blood sugar levels can occur, potentially leading to or exacerbating diabetes.

References

  1. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on June 2022] [ Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.6658.pdf
  2. Jan Hasskarl; Everolimus; Recent Results in Cancer Research; Published on 2018; Accessed on 18/03/2023; https://pubmed.ncbi.nlm.nih.gov/30069763/
  3. Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [ Revised on July 2012] [ Accessed on 18th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted therapy: tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1743.
  5. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878 – 882.

Disclaimer

Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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