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Advacan 0.5mg Tablet Original price was: ₹1,095.00.Current price is: ₹850.00.
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Evergraf 0.25mg Tablet
Evergraf 0.25mg Tablet Original price was: ₹700.59.Current price is: ₹560.47.

Everotas 0.25mg Tablet

Original price was: ₹469.00.Current price is: ₹375.20.

Prescription Required

Salt : Everolimus

Manufacturer : Intas Pharmaceuticals Ltd

Packing : 10 Tablet In A Strip

Description

PRODUCT INTRODUCTION

Everotas 0.25mg Tablet, a medication developed to address various neurological conditions, embodies the convergence of cutting-edge pharmaceutical science and the pursuit of enhanced quality of life. Manufactured with precision and care, each tablet contains 0.25 milligrams of the active ingredient, Everolimus. Everotas belongs to a class of medications known as mammalian target of rapamycin (mTOR) inhibitors, which play a crucial role in regulating cell growth, proliferation, and survival.

This tablet is meticulously formulated to ensure consistent efficacy and safety. Packaged in blister packs to maintain potency, Everotas tablets are easily identifiable with their distinctive blue color and elliptical shape. The packaging includes comprehensive instructions for use, ensuring that patients receive optimal therapeutic benefits while minimizing the risk of adverse effects.

USES OF Everotas 0.25mg Tablet

Everotas 0.25mg Tablet is prescribed for various medical conditions, primarily targeting neurological disorders and certain types of cancer. Its primary indications include:

  1. Organ Transplant Rejection Prophylaxis: Everotas is utilized in transplant medicine to prevent rejection of transplanted organs, such as kidneys or liver, by suppressing the recipient’s immune response. By inhibiting mTOR pathways, it helps maintain the delicate balance between immune tolerance and immune response, thereby prolonging the lifespan of transplanted organs.
  2. Tuberous Sclerosis Complex (TSC): Everotas demonstrates efficacy in the treatment of TSC, a genetic disorder characterized by the growth of benign tumors in various organs, including the brain, kidneys, heart, eyes, lungs, and skin. By inhibiting the abnormal cell proliferation associated with TSC, Everotas helps manage symptoms and improve overall patient outcomes.
  3. Advanced Renal Cell Carcinoma (RCC): Everotas is indicated for the treatment of advanced RCC, a type of kidney cancer that has spread to other parts of the body. It inhibits the growth of cancer cells by disrupting signaling pathways involved in cell proliferation and angiogenesis, thereby slowing disease progression and improving survival rates.

BENEFITS OF Everotas 0.25mg Tablet

Everotas 0.25mg Tablet offers several notable benefits, making it a valuable therapeutic option for patients and healthcare providers alike:

  1. Effective Immunomodulation: By selectively targeting mTOR pathways, Everotas modulates the immune response, thereby reducing the risk of organ rejection in transplant recipients while minimizing the need for high-dose immunosuppressive therapy. This promotes better long-term graft survival and reduces the incidence of transplant-related complications.
  2. Tumor Growth Inhibition: In patients with TSC and advanced RCC, Everotas demonstrates significant antitumor activity by inhibiting the aberrant cell proliferation and angiogenesis characteristic of these conditions. This leads to tumor regression, stabilization, or slower progression, thereby improving overall disease control and quality of life.
  3. Disease Symptom Management: Everotas helps alleviate symptoms associated with TSC, such as seizures, cognitive impairment, skin lesions, and renal dysfunction, enabling patients to lead more fulfilling lives with reduced disease burden. Similarly, in advanced RCC, it may alleviate pain, improve physical functioning, and enhance overall well-being by controlling cancer-related symptoms.
  4. Convenient Oral Administration: Everotas is available in tablet form for oral administration, offering convenience and flexibility to patients. With once-daily dosing, it simplifies treatment regimens and enhances medication adherence, ensuring consistent therapeutic levels in the bloodstream for optimal efficacy.

SIDE EFFECTS OF Everotas 0.25mg Tablet

While Everotas 0.25mg Tablet confers numerous therapeutic benefits, it may also be associated with certain adverse effects, which should be carefully monitored by healthcare professionals:

  1. Immunosuppression: Everotas may increase the risk of infections due to its immunosuppressive effects, including bacterial, viral, fungal, and opportunistic infections. Patients should be vigilant for signs of infection, such as fever, cough, sore throat, and flu-like symptoms, and promptly report any concerns to their healthcare provider.
  2. Metabolic Disturbances: Everotas can disrupt metabolic homeostasis, leading to hyperglycemia, hyperlipidemia, and electrolyte imbalances. Regular monitoring of blood glucose, lipid levels, and electrolyte concentrations is essential to detect and manage these metabolic complications promptly.
  3. Gastrointestinal Symptoms: Common gastrointestinal side effects of Everotas include nausea, diarrhea, vomiting, and stomatitis. These symptoms can typically be managed with supportive care measures, such as antiemetic medications, dietary modifications, and oral hygiene practices.
  4. Dermatological Reactions: Everotas may cause dermatological adverse reactions, such as rash, acne, dry skin, and mucositis. Patients should practice good skincare habits, avoid prolonged sun exposure, and use sunscreen to minimize the risk of dermatological complications.
  5. Renal Dysfunction: Everotas has the potential to impair renal function, leading to proteinuria, hypertension, and renal insufficiency. Regular monitoring of renal function through laboratory tests, including serum creatinine and urine protein levels, is recommended to detect and manage renal complications promptly.

References

  1. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on June 2022] [ Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.6658.pdf
  2. Jan Hasskarl; Everolimus; Recent Results in Cancer Research; Published on 2018; Accessed on 18/03/2023; https://pubmed.ncbi.nlm.nih.gov/30069763/
  3. Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [ Revised on July 2012] [ Accessed on 18th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted therapy: tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1743.
  5. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878 – 882.

Disclaimer

Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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