

imatib 100mg tablet
₹548.00 Original price was: ₹548.00.₹280.00Current price is: ₹280.00.
PRODUCT INTRODUCTION
Imatib 100mg Tablet, a groundbreaking medication in the realm of oncology, represents a beacon of hope for patients battling certain types of cancers, particularly chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). Manufactured by Novartis Pharmaceuticals, Imatib encapsulates the potent compound Imatinib Mesylate, which belongs to a class of medications known as tyrosine kinase inhibitors (TKIs). These tablets are meticulously formulated to target specific abnormal proteins within cancer cells, hindering their growth and proliferation.
USES of Imatib 100mg Tablet
Imatib 100mg Tablet is primarily prescribed for the treatment of two main conditions:
a. Chronic Myeloid Leukemia (CML): CML is a form of blood cancer characterized by the abnormal growth of white blood cells in the bone marrow. Imatib works by inhibiting the activity of the BCR-ABL protein, which is responsible for the uncontrolled proliferation of leukemic cells. By targeting this protein, Imatib helps in suppressing the growth of cancerous cells, thereby slowing down the progression of CML and improving patient outcomes.
b. Gastrointestinal Stromal Tumors (GISTs): GISTs are rare tumors that develop in the gastrointestinal tract. Imatib has demonstrated remarkable efficacy in treating GISTs by inhibiting the activity of the KIT protein, which is often mutated in these tumors. By blocking the aberrant signaling pathways mediated by KIT, Imatib effectively shrinks the tumors, alleviates symptoms, and prolongs survival in patients with GISTs.
BENEFITS OF Imatib 100mg Tablet
The introduction of Imatib 100mg Tablet has revolutionized the landscape of cancer treatment, offering a myriad of benefits to patients:
a. Improved Survival Rates: Clinical studies have shown that Imatib significantly prolongs overall survival and progression-free survival in patients with CML and GISTs. By effectively targeting the underlying molecular mechanisms driving these cancers, Imatib helps patients live longer and healthier lives.
b. Enhanced Quality of Life: Imatib therapy is associated with symptom relief and improvement in the quality of life for patients suffering from CML and GISTs. By reducing tumor burden and preventing disease progression, Imatib alleviates symptoms such as fatigue, pain, and gastrointestinal discomfort, allowing patients to enjoy a better quality of life.
c. Reduced Risk of Disease Progression: Imatib has been shown to substantially reduce the risk of disease recurrence or progression in patients who have undergone surgery for GISTs. Adjuvant treatment with Imatib helps prevent the growth of residual tumor cells, lowering the likelihood of tumor recurrence and improving long-term outcomes.
d. Targeted Therapy with Fewer Side Effects: Unlike conventional chemotherapy, which indiscriminately kills both cancerous and healthy cells, Imatib exerts its effects in a targeted manner by specifically inhibiting the activity of abnormal proteins within cancer cells. This targeted approach minimizes the risk of systemic toxicity and debilitating side effects commonly associated with traditional cancer treatments, such as hair loss, nausea, and immune suppression.
SIDE EFFECTS of Imatib 100mg Tablet
While Imatib is generally well-tolerated, it may cause some side effects in certain individuals. Common side effects of Imatib 100mg Tablet include:
a. Gastrointestinal Disturbances: Nausea, vomiting, diarrhea, and abdominal pain are among the most commonly reported side effects of Imatib therapy. These symptoms are usually mild to moderate in severity and can be managed with supportive care measures such as antiemetic medications and dietary modifications.
b. Fatigue and Weakness: Some patients may experience fatigue, weakness, or lethargy during Imatib treatment. These symptoms can impact daily functioning and may require adjustments in activity levels or lifestyle habits to manage effectively.
c. Edema: Imatib therapy may cause fluid retention and peripheral edema in some individuals. Swelling of the extremities, particularly the ankles and feet, is a common manifestation of this side effect. Monitoring of fluid intake and the use of diuretic medications may be necessary to alleviate edema symptoms.
d. Hematologic Abnormalities: Imatib can affect blood cell counts, leading to abnormalities such as anemia, thrombocytopenia, or neutropenia. Regular monitoring of blood counts is essential during Imatib therapy to detect and manage any hematologic complications promptly.
e. Liver Toxicity: Rarely, Imatib may cause liver enzyme elevations or hepatotoxicity, manifesting as jaundice, abdominal pain, or abnormal liver function tests. Close monitoring of liver function is recommended, and dose adjustments may be necessary in patients with pre-existing liver disease.
In conclusion, Imatib 100mg Tablet represents a paradigm shift in the treatment of certain types of cancers, offering patients a highly effective and well-tolerated therapeutic option. By targeting specific molecular abnormalities within cancer cells, Imatib provides significant clinical benefits, including improved survival rates, enhanced quality of life, and reduced risk of disease progression. While side effects may occur, they are generally manageable and outweighed by the profound therapeutic benefits of this groundbreaking medication. Imatib stands as a shining example of precision medicine in oncology, heralding a new era of hope and progress in the fight against cancer.
References
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Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1732-34.
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Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 692-94.
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