

Mabtas 500mg Injection
₹42,658.94 Original price was: ₹42,658.94.₹9,500.00Current price is: ₹9,500.00.
Prescription Required
Cold chain
Salt : Rituximab (500mg)
Manufacturer : Intas Pharmaceuticals Ltd
Packing : 50 ml in 1 vial
Prepaid Only, Non-Returnable
PRODUCT INTRODUCTION
Mabtas 500mg Injection is a potent medication belonging to the class of monoclonal antibodies. This medicine is formulated to target specific proteins in the body’s immune system, thereby modulating its response. Manufactured under stringent quality standards, Mabtas is a breakthrough in the realm of immunotherapy. It is designed to offer targeted therapy for various autoimmune disorders and certain types of cancers.
USES OF MABTAS 500MG INJECTION
Mabtas 500mg Injection finds application in the treatment of several medical conditions, primarily autoimmune disorders and certain malignancies. Some of its key uses include:
- Rheumatoid Arthritis (RA): Mabtas is effective in managing symptoms and slowing down the progression of rheumatoid arthritis, a chronic inflammatory disorder that primarily affects the joints.
- Ankylosing Spondylitis: This medication is prescribed to alleviate the symptoms of ankylosing spondylitis, a type of arthritis that mainly impacts the spine.
- Psoriatic Arthritis: Mabtas is indicated for the treatment of psoriatic arthritis, a condition characterized by joint inflammation and skin lesions.
- Crohn’s Disease: It is used in the management of Crohn’s disease, a type of inflammatory bowel disease that causes inflammation of the digestive tract.
- Ulcerative Colitis: Mabtas helps in inducing and maintaining remission in patients suffering from ulcerative colitis, a chronic inflammatory condition affecting the colon and rectum.
- Non-Hodgkin’s Lymphoma: In certain cases of non-Hodgkin’s lymphoma, Mabtas is employed as part of the therapeutic regimen to target specific cancer cells and inhibit their growth.
- Chronic Lymphocytic Leukemia: It is also utilized in the treatment of chronic lymphocytic leukemia, a type of cancer affecting the blood and bone marrow.
BENEFITS OF MABTAS 500MG INJECTION
The administration of Mabtas 500mg Injection offers several benefits to patients suffering from the aforementioned medical conditions:
- Targeted Therapy: Mabtas acts specifically on certain proteins involved in the immune response, providing targeted therapy with minimal impact on healthy tissues.
- Symptom Relief: By modulating the immune system, Mabtas helps alleviate the symptoms associated with autoimmune disorders such as joint pain, inflammation, and bowel disturbances.
- Disease Modification: In chronic conditions like rheumatoid arthritis and Crohn’s disease, Mabtas has the potential to modify the course of the disease, slowing down its progression and reducing the risk of complications.
- Improved Quality of Life: By effectively managing symptoms and controlling disease activity, Mabtas contributes to an improved quality of life for patients, enabling them to engage in daily activities with greater comfort and functionality.
- Combination Therapy: Mabtas can be used alone or in combination with other medications, providing flexibility in treatment approaches and enhancing therapeutic outcomes.
SIDE EFFECTS OF MABTAS 500MG INJECTION
While Mabtas is generally well-tolerated, like any medication, it may cause certain side effects in some individuals. These side effects can vary in severity and may include:
- Infusion Reactions: Some patients may experience infusion-related reactions during or shortly after the administration of Mabtas, characterized by symptoms like fever, chills, nausea, headache, and skin rashes.
- Increased Risk of Infections: Mabtas can suppress the immune system, leading to an increased susceptibility to infections. Patients should be monitored closely for signs of infections and appropriate measures should be taken if any occur.
- Hypersensitivity Reactions: In rare cases, Mabtas may trigger allergic reactions such as hives, itching, swelling, and difficulty breathing. Immediate medical attention is necessary if any signs of a severe allergic reaction develop.
- Hematological Disorders: Mabtas may affect blood cell counts, leading to conditions like neutropenia (low white blood cell count) and thrombocytopenia (low platelet count), which can increase the risk of bleeding and infections.
- Liver Toxicity: Rarely, Mabtas may cause liver damage, manifesting as elevated liver enzymes and jaundice. Regular liver function tests are recommended during treatment with Mabtas to monitor for any signs of liver toxicity.
- Other Common Side Effects: Other common side effects of Mabtas may include fatigue, diarrhea, abdominal pain, muscle aches, and respiratory infections.
REFERENCES
1. KD. Tripathi. Chemotherapy of Neoplastic Diseases. Essentials of Medical Pharmacology. 7th Edition. Page – 872.
2. Nazma Hanif, Faiz Anwer. Rituximab. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed central. September 2022. [Accessed on 28th January 2023]Â https://www.ncbi.nlm.nih.gov/books/NBK564374/
3. Roche Products Ltd. MabThera 100 mg and 500 mg concentrate solution for infusion. Rituximab. Electronics Medicines Compendium. [Revised in January 2022]. [Accessed on 28th January 2023]Â https://www.medicines.org.uk/emc/files/pil.3801.pdf
4. Biogen and Genentech USA, Inc. RITUXAN® (rituximab) injection, for intravenous use. U.S. Food and Drug Administration. [Revised in December 2021]. [Accessed on 28th January 2023] https://www.gene.com/download/pdf/rituxan_prescribing.pdf
5. Biogen and Genentech USA, Inc. Rituxan. Rituximab. [Accessed on 28th January 2023]Â https://www.rituxan.com/
6. Central Drugs Standard Control Organization. Rituximab (finished formulation import). July 2000. [Accessed on 28th January 2023]Â https://cdscoonline.gov.in/CDSCO/Drugs
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