Nab Tortaxel 100Mg Injection

PRODUCT INTRODUCTION

Nab Tortaxel 100mg Injection is a medication belonging to the class of drugs known as taxanes. It is a formulation of nanoparticle albumin-bound (nab) paclitaxel, a chemotherapy drug used to treat various types of cancers. This formulation utilizes albumin, a protein found in blood, to deliver the medication directly to cancer cells, enhancing its effectiveness while minimizing side effects.

USES OF Nab Tortaxel 100Mg Injection

Nab Tortaxel 100mg Injection is primarily prescribed for the treatment of:

• Breast Cancer: It is used in both early-stage and metastatic breast cancer, either as a single agent or in combination with other chemotherapy drugs.
• Pancreatic Cancer: Nab Tortaxel is indicated for the treatment of metastatic pancreatic cancer, often in combination with other chemotherapy medications.
• Non-Small Cell Lung Cancer (NSCLC): It may be prescribed for patients with advanced NSCLC, particularly in cases where other treatments have not been effective.

BENEFITS OF Nab Tortaxel 100Mg Injection

• Enhanced Efficacy: The nanoparticle albumin-bound formulation allows for targeted delivery of paclitaxel to cancer cells, potentially improving treatment outcomes.
• Convenience: Nab Tortaxel can be administered intravenously, typically in a hospital or clinic setting, making it convenient for patients undergoing chemotherapy.
• Versatility: It is effective in treating various types of cancers, offering a versatile treatment option for patients with different cancer diagnoses.
• Potential for Combination Therapy: Nab Tortaxel can be used in combination with other chemotherapy drugs, targeted therapies, or immunotherapies, providing physicians with flexibility in treatment planning.

SIDE EFFECTS OF Nab Tortaxel 100Mg Injection

While Nab Tortaxel is generally well-tolerated, like all medications, it can cause side effects. Common side effects may include:

• Bone marrow suppression: This can lead to a decrease in white blood cells (neutropenia), red blood cells (anemia), and platelets (thrombocytopenia), increasing the risk of infections, fatigue, and bleeding tendencies.
• Peripheral neuropathy: This condition can cause tingling, numbness, or pain in the hands and feet, which may be temporary or persistent.
• Hair loss: Nab Tortaxel may cause temporary hair loss or thinning, although this side effect is usually reversible once treatment is completed.
• Gastrointestinal disturbances: Patients may experience nausea, vomiting, diarrhea, or constipation. These symptoms are usually manageable with medications and lifestyle modifications.
• Hypersensitivity reactions: Some patients may develop allergic reactions to Nab Tortaxel, which can manifest as rash, itching, difficulty breathing, or swelling of the face, lips, or tongue. These reactions require immediate medical attention.

REFERENCES

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2. Maela C. Farrar; Tibb F. Jacobs. Paclitaxel.  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in May 2022] [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/books/NBK536917

3. Kyohei Kanematsu, Hironori Tsujimoto,∗ Shinsuke Nomura, Hiroyuki Horiguchi, Nozomi Ito, Kenji Yamazaki, Shuichi Hiraki, Suefumi Aosasa, Junji Yamamoto and Kazuo Hase. Weekly paclitaxel therapy for gastric cancer in patients with renal dysfunction: A case report. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in September 2016] [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021784/

4. Denise A Yardley. Taxanes in the elderly patient with metastatic breast cancer. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in September 2015] [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567240/

5. Fresenius Kabi India Pvt. Ltd. Paclitaxel. [Accessed on 7th October 2021] https://www.fresenius-kabi.com/in/products/paclitaxel

6. Dr. Reddy’s Laboratories Ltd. Mitotax Inj. 250mg. [Accessed on 7th October 2021] https://www.drreddys.com/russia-en/products/product-list/m/mitotax-inj-250-mg/

7. Intas Pharmaceuticals Ltd. CYTAX-200. [Accessed on 7th October 2021] https://www.intaspharma.com/products/

8. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in December 2019] [Accessed on 7th October 2021] https://www.medicines.org.uk/emc/files/pil.6076.pdf