

Nitnib 12.5mg Capsule
₹495.00 Original price was: ₹495.00.₹396.00Current price is: ₹396.00.
Prescription Required
Salt : Sunitinib
Manufacturer : Zydus Cadila
Packing : 7 Capsule In A Strip
PRODUCT INTRODUCTION
Nitnib 12.5mg Capsule is a medication primarily composed of Nilotinib, a tyrosine kinase inhibitor (TKI) utilized in the treatment of certain types of cancer, notably chronic myeloid leukemia (CML). This oral medication is formulated to specifically target cancer cells, inhibiting their growth and proliferation, thus aiding in the management of the disease. Nitnib belongs to the class of medications known as protein kinase inhibitors, which work by blocking the action of abnormal proteins that signal cancer cells to multiply.
USES OF Nitnib 12.5mg Capsule
Nitnib 12.5mg Capsule is primarily prescribed for the treatment of chronic myeloid leukemia (CML), a type of cancer that affects the blood and bone marrow. CML is characterized by the overproduction of white blood cells, leading to various symptoms such as fatigue, weight loss, and abdominal discomfort. Nitnib helps to control the progression of CML by targeting and inhibiting the activity of the abnormal protein produced by the Philadelphia chromosome, a genetic mutation commonly associated with this type of leukemia. By doing so, Nitnib helps to reduce the number of cancer cells in the body and improve symptoms associated with CML.
BENEFITS OF Nitnib 12.5mg Capsule
The primary benefit of Nitnib 12.5mg Capsule is its efficacy in the treatment of chronic myeloid leukemia (CML). By specifically targeting cancer cells and inhibiting their growth, Nitnib helps to slow down the progression of the disease and improve overall prognosis. Additionally, Nitnib is administered orally, making it convenient for patients to take and adhere to their treatment regimen. Furthermore, Nitnib has been shown to be effective in patients who have developed resistance to other TKIs, providing an alternative treatment option for those who have not responded well to previous therapies.
SIDE EFFECTS OF Nitnib 12.5mg Capsule
While Nitnib 12.5mg Capsule is generally well-tolerated, like all medications, it may cause certain side effects in some individuals. Common side effects of Nitnib may include nausea, vomiting, diarrhea, headache, fatigue, and muscle cramps. These side effects are usually mild to moderate in nature and often resolve on their own or with symptomatic treatment. However, patients experiencing severe or persistent side effects should consult their healthcare provider for further evaluation and management.
In addition to the common side effects mentioned above, Nitnib may also cause more serious adverse reactions in some patients. These may include:
- Cardiovascular Effects: Nitnib has been associated with QT interval prolongation, which can increase the risk of abnormal heart rhythms. Patients with pre-existing cardiovascular conditions or those taking other medications that also prolong the QT interval may be at higher risk.
- Liver Toxicity: Nitnib can cause liver damage, leading to elevated liver enzymes and liver function tests. Patients may experience symptoms such as jaundice, abdominal pain, and dark urine. Regular monitoring of liver function is essential during treatment with Nitnib.
- Fluid Retention: Some patients may experience fluid retention while taking Nitnib, leading to swelling in the legs, ankles, or around the eyes. This can be managed with diuretic medications and dietary modifications.
- Pancreatitis: In rare cases, Nitnib may cause inflammation of the pancreas (pancreatitis), leading to abdominal pain, nausea, and vomiting. Patients should seek medical attention if they experience these symptoms.
References
- Pfizer, U.S Drug and food safety administration (FDA), [Revised on Dec 2018], [Accessed on 5th April 2023],
https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021938s035lbl.pdf - Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
- Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo, Tyrosine Kinase Inhibitors, [Revised on 21st Jan 2021] [Accessed on 5th April 2023],
https://www.ncbi.nlm.nih.gov/books/NBK563322/ - Pfizer, Electronic Medicines Compendium (EMC) [Revised on Mar 2021] [Accessed on 5th April 2023],  https://www.medicines.org.uk/emc/files/pil.7966.pdf
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936
Disclaimer
Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.
Shipping Policy
We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.
Delivery
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Your purchases may reach you from various locations in more than one package. But rest assured, you will be charged one delivery fee for the entire order. As soon as your package ships, we will email you your package tracking information.
We are bound in coverage by their reach even though we use some of India’s largest logistics companies for shipping. In case your address is in a location not served by them we would contact you to find an alternative solution to make your products reach you.
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