

Spnib 50mg Tablet
₹3,401.00 Original price was: ₹3,401.00.₹2,450.00Current price is: ₹2,450.00.
Prescription Required
Salt : Dasatinibu
Manufacturer : Zydus Cadila
Packing : 60 Tablet(S) In A Bottle
Product Introduction
Spnib 50mg Tablet is a prescription medication that has gained recognition for its efficacy in treating certain types of cancer. It belongs to a class of drugs known as tyrosine kinase inhibitors, specifically targeting the BCR-ABL tyrosine kinase enzyme. This enzyme is known for its role in the growth and proliferation of cancer cells. Spnib 50mg is often prescribed for the treatment of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL), particularly when these conditions exhibit the Philadelphia chromosome positive (Ph+) status.
Uses of Spnib 50mg Tablet
The primary indication of Spnib 50mg Tablet is the treatment of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). These are types of cancers that affect the bone marrow and blood, characterized by an overproduction of certain types of white blood cells. Spnib 50mg works effectively in cases where the cancer cells express the BCR-ABL fusion protein, which results from the Philadelphia chromosome abnormality.
- Chronic Myeloid Leukemia (CML): For patients suffering from CML, Spnib 50mg helps in managing the proliferation of cancerous cells. It is used in various phases of CML, including chronic, accelerated, and blast phases, depending on the patient’s specific condition and physician’s advice.
- Acute Lymphoblastic Leukemia (ALL): In the case of ALL, Spnib 50mg is typically used when other treatments have not been effective or as a first-line treatment in specific cases where the Philadelphia chromosome is present.
Additionally, Spnib 50mg may be used in treating other conditions as determined by a healthcare provider, adhering strictly to the indications approved by regulatory authorities.
Benefits of Spnib 50mg Tablet
The use of Spnib 50mg Tablet offers significant benefits for patients diagnosed with specific types of leukemia:
- Targeted Therapy: As a tyrosine kinase inhibitor, Spnib 50mg specifically targets cancerous cells without affecting many of the healthy cells in the body. This results in fewer side effects compared to traditional chemotherapy.
- High Efficacy: Clinical trials and patient outcomes have shown that Spnib 50mg is highly effective in controlling the growth of cancer cells, especially in the early and middle stages of the diseases.
- Improves Survival Rates: With its targeted action, Spnib 50mg has been associated with improved survival rates among patients suffering from CML and Ph+ ALL.
- Oral Administration: Being available in tablet form, it offers convenience in administration compared to intravenous therapies, leading to better adherence to treatment schedules.
Side Effects of Spnib 50mg Tablet
While Spnib 50mg is effective in treating certain cancers, it may cause side effects that vary from mild to severe. Patients are advised to monitor for any adverse reactions and consult their healthcare provider if they experience significant discomfort. Common side effects include:
- Digestive Issues: Nausea, vomiting, diarrhea, and abdominal pain.
- Blood Cell Count Changes: Thrombocytopenia (low platelet count), anemia (low red blood cell count), and neutropenia (low white blood cell count) can occur.
- Musculoskeletal Pain: Cramps and muscle pain are relatively common.
- Fluid Retention: Patients may experience swelling around the eyes or in the extremities.
- Fatigue: A common effect that can vary in intensity.
- Liver Function Changes: Elevated liver enzymes may indicate an impact on liver function, requiring monitoring and potential adjustment of dosage.
More severe side effects, although less common, can include cardiovascular problems, pulmonary issues, and severe liver dysfunction. It is crucial for patients to have regular follow-ups with their healthcare providers to monitor the drug’s efficacy and manage any adverse effects efficiently.
References
- Bristol-Myers Squibb Pharma, Electronic Medicines Compendium (EMC), [Revised on Mar 2022] [Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.7745.pdf
- Bristol-Myers Squibb Company, [Revised on Jun 2021] [Accessed on 1st Dec 2022], https://packageinserts.bms.com/ppi/ppi_sprycel.pdf
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Disclaimer
Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.
Shipping Policy
We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.
Delivery
The delivery times are subject to location, distance, and our logistics partners. We are not liable for any delays in delivery by the courier company/postal authorities but will help you track down a package through our partner courier services.
Your purchases may reach you from various locations in more than one package. But rest assured, you will be charged one delivery fee for the entire order. As soon as your package ships, we will email you your package tracking information.
We are bound in coverage by their reach even though we use some of India’s largest logistics companies for shipping. In case your address is in a location not served by them we would contact you to find an alternative solution to make your products reach you.
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