Stalix D (10+100) Tablet

PRODUCT INTRODUCTION

STALIX D 10+100 Tablet is an oral anti-diabetic medication prescribed primarily to manage Type 2 diabetes mellitus. It is a combination drug that contains two active ingredients: Teneligliptin (10 mg) and Dapagliflozin (100 mg). These two components work in synergy to lower blood sugar levels in people whose diabetes cannot be adequately controlled by diet and exercise alone.

Teneligliptin belongs to a class of drugs known as DPP-4 inhibitors (Dipeptidyl Peptidase-4 Inhibitors). It works by increasing the levels of incretin hormones, which in turn help regulate insulin production in response to meals, suppress glucagon secretion, and delay gastric emptying. This helps in reducing blood glucose levels.

Dapagliflozin is part of the SGLT2 inhibitors (Sodium-Glucose Co-Transporter 2 Inhibitors) family. It reduces glucose reabsorption in the kidneys, allowing excess glucose to be excreted through urine, thereby lowering blood sugar levels.

Together, these two drugs provide a comprehensive approach to glucose regulation, making STALIX D 10+100 Tablet a highly effective therapy for patients with uncontrolled Type 2 diabetes. However, it should be noted that this medicine is not used to treat Type 1 diabetes or diabetic ketoacidosis.

USES OF STALIX D 10+100 Tablet

The primary use of STALIX D 10+100 Tablet is to manage Type 2 diabetes mellitus. It is often prescribed to patients who have not achieved adequate glycemic control with metformin or other single-therapy medications. It works to reduce fasting and postprandial (after meal) blood glucose levels. While its primary indication is glucose management, the medication also offers secondary benefits such as slight weight reduction and lowered blood pressure, particularly due to the dapagliflozin component.

This drug should be taken as part of a broader diabetes management plan that includes diet, exercise, and regular monitoring of blood glucose levels.

BENEFITS OF STALIX D 10+100 Tablet

• Effective Blood Glucose Control: The combination of Teneligliptin and Dapagliflozin in STALIX D 10+100 Tablet ensures a dual approach to blood sugar regulation. Teneligliptin increases insulin secretion, and Dapagliflozin reduces glucose reabsorption in the kidneys, together offering effective glycemic control.

• Weight Loss: Dapagliflozin, being an SGLT2 inhibitor, helps in mild weight loss, which is beneficial for patients who are overweight or obese—common conditions in people with Type 2 diabetes.

• Improved Cardiovascular Health: Dapagliflozin has been shown to have potential cardiovascular benefits. For patients with heart issues, this medication may reduce the risk of heart failure and other cardiovascular conditions.

• Flexible Combination Therapy: The tablet can be used alone or in combination with other anti-diabetic drugs like metformin, insulin, or sulfonylureas. This flexibility allows doctors to tailor treatment according to individual patient needs.

• Convenient Dosing: Unlike insulin or other injectables, STALIX D 10+100 Tablet is an oral medication, making it easier for patients to adhere to their treatment regimen.

SIDE EFFECTS OF STALIX D 10+100 Tablet

Like all medications, STALIX D 10+100 Tablet may cause side effects, although not everyone experiences them. Common and rare side effects associated with the active ingredients include:

• Common Side Effects:
  • Urinary Tract Infections (UTIs): Dapagliflozin can increase glucose excretion through the urine, creating an environment where bacteria can thrive, thus increasing the risk of UTIs.
  • Increased Urination: Dapagliflozin's mechanism of action can cause frequent urination due to increased glucose excretion.
  • Hypoglycemia: Although rare, combining STALIX D 10+100 with other anti-diabetic agents like insulin or sulfonylureas can cause a drop in blood glucose levels, leading to hypoglycemia.
  • Nausea: Teneligliptin can sometimes cause gastrointestinal disturbances like nausea, though this is generally mild.
  • Thirst: Excessive urination can lead to dehydration, making you feel thirstier than usual.
• Rare but Serious Side Effects:
  • Ketoacidosis: In rare cases, the use of dapagliflozin has been linked to diabetic ketoacidosis, a potentially life-threatening condition that results from the accumulation of acids in the blood.
  • Severe Allergic Reactions: Some people may experience severe allergic reactions to Teneligliptin or Dapagliflozin, including swelling, difficulty breathing, or severe skin reactions.
  • Lactic Acidosis: Though more common with metformin, combining certain diabetic drugs can increase the risk of lactic acidosis, a serious condition where lactic acid builds up in the blood.
  • Kidney Function Decline: Although rare, dapagliflozin can affect kidney function, particularly in patients who already have impaired renal function.