

Sutib 50mg Capsule
₹1,750.00 Original price was: ₹1,750.00.₹1,400.00Current price is: ₹1,400.00.
Prescription Required
Salt : Sunitinib
Manufacturer : Glenmark Pharmaceuticals Ltd
Packing : 7 Capsule In A Strip
Product Introduction
Sutib 50mg Capsule is a medication primarily used in the treatment of various types of cancer. It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs), which work by blocking specific enzymes (tyrosine kinases) that play a crucial role in the signaling pathways involved in the growth and spread of cancer cells. Sutib is the trade name for the generic drug sunitinib, which has been widely recognized for its efficacy in targeting cancerous cells and inhibiting tumor growth.
Manufactured by several pharmaceutical companies, Sutib 50mg Capsule is typically prescribed for the treatment of gastrointestinal stromal tumors (GIST), advanced renal cell carcinoma (RCC), and pancreatic neuroendocrine tumors (pNET). The capsule form of the drug allows for oral administration, making it a convenient option for patients undergoing long-term cancer therapy.
Uses of Sutib 50mg Capsule
Sutib 50mg Capsule is utilized in the treatment of several types of cancers, primarily:
- Gastrointestinal Stromal Tumors (GIST): Sutib is often prescribed for patients with GIST who are resistant to or cannot tolerate imatinib, another TKI. GIST is a type of tumor that occurs in the digestive tract, commonly starting in the stomach or small intestine.
- Advanced Renal Cell Carcinoma (RCC): Sutib is used to treat advanced RCC, which is a type of kidney cancer. It is particularly useful in cases where the cancer has spread to other parts of the body.
- Pancreatic Neuroendocrine Tumors (pNET): This medication is also effective for treating pNET, which are rare tumors originating in the hormone-producing cells of the pancreas. Sutib is typically used in advanced cases where the tumor cannot be surgically removed.
Benefits of Sutib 50mg Capsule
The primary benefit of Sutib 50mg Capsule lies in its ability to slow the progression of cancer and improve survival rates in patients with specific types of tumors. The benefits of this medication include:
- Targeted Action: Sutib specifically targets and inhibits tyrosine kinases, enzymes that are involved in the growth and spread of cancer cells. This targeted action helps in effectively managing cancer progression.
- Improved Survival Rates: Clinical studies have shown that Sutib can significantly extend progression-free survival in patients with advanced RCC and GIST. It helps in delaying the progression of the disease and, in some cases, can lead to tumor shrinkage.
- Convenient Administration: As an oral capsule, Sutib offers a non-invasive treatment option that can be easily incorporated into a patient’s daily routine, enhancing compliance and convenience compared to intravenous therapies.
- Symptom Management: In addition to controlling tumor growth, Sutib can also help alleviate symptoms associated with cancer, thereby improving the quality of life for patients undergoing treatment.
Side Effects of Sutib 50mg Capsule
While Sutib 50mg Capsule is effective in treating certain cancers, it is associated with a range of potential side effects. The severity and occurrence of these side effects can vary from patient to patient. Common side effects include:
- Gastrointestinal Issues: Patients may experience nausea, vomiting, diarrhea, and loss of appetite. These symptoms are often manageable with supportive care and medication adjustments.
- Fatigue: Many patients report feeling unusually tired or weak. Fatigue is a common side effect that can impact daily activities and overall well-being.
- Skin Changes: Sutib can cause changes in skin color, dryness, rash, and hand-foot syndrome (redness, swelling, and pain on the palms of the hands or soles of the feet).
- Hypertension: An increase in blood pressure is a known side effect of Sutib. Regular monitoring and management with antihypertensive medications may be necessary.
- Hematologic Toxicity: This includes a decrease in white blood cells (neutropenia), red blood cells (anemia), and platelets (thrombocytopenia). Patients require regular blood tests to monitor their blood cell counts.
- Mouth Sores: Painful sores or ulcers can develop in the mouth, leading to difficulties in eating and drinking.
- Liver Function: Sutib can cause elevations in liver enzymes, indicating liver dysfunction. Regular liver function tests are recommended to monitor and manage this potential side effect.
- Cardiotoxicity: Although rare, Sutib can have effects on the heart, including heart failure and myocardial infarction. Patients with pre-existing heart conditions require careful monitoring.
- Other Side Effects: These can include hypothyroidism, altered taste sensation, and changes in hair color.
References
- Pfizer, U.S Drug and food safety administration (FDA), [Revised on Dec 2018], [Accessed on 5th April 2023],
https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021938s035lbl.pdf - Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
- Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo, Tyrosine Kinase Inhibitors, [Revised on 21st Jan 2021] [Accessed on 5th April 2023],
https://www.ncbi.nlm.nih.gov/books/NBK563322/ - Pfizer, Electronic Medicines Compendium (EMC) [Revised on Mar 2021] [Accessed on 5th April 2023],  https://www.medicines.org.uk/emc/files/pil.7966.pdf
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936
Disclaimer
Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.
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