Product Introduction

Tresiba 100 Units/ml Penfill is a long-acting insulin formulation used to manage blood glucose levels in patients with diabetes mellitus. It is designed to provide consistent, basal insulin coverage with a duration of action of up to 42 hours. Tresiba is a clear, colorless solution available in a prefilled pen format, making it convenient for subcutaneous administration. Each Penfill contains 3 ml of insulin degludec, with a concentration of 100 units/ml.

The insulin in Tresiba is an ultra-long-acting basal insulin that helps to maintain stable blood glucose levels throughout the day and night. Tresiba is typically used in combination with rapid-acting insulin or other antidiabetic medications to achieve optimal glycemic control.

Uses of Tresiba 100 Units/ml Penfill (3ml Each)

Tresiba 100 Units/ml Penfill is primarily prescribed for the management of type 1 and type 2 diabetes mellitus. Its main uses include:

• Basal Insulin Therapy: Tresiba is used to provide a steady level of insulin over an extended period, helping to control blood glucose levels between meals and overnight.
• Glycemic Control: It aids in the long-term control of blood glucose levels in patients who need basal insulin coverage. Tresiba helps in achieving better glycemic control and reducing the risk of both hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).
• Adjunct to Mealtime Insulin: In type 1 diabetes or insulin-dependent type 2 diabetes, Tresiba is often used in combination with mealtime insulin (rapid-acting or short-acting) to manage blood glucose levels more effectively.

Benefits of Tresiba 100 Units/ml Penfill (3ml Each)

Tresiba offers several advantages for patients with diabetes:

• Extended Duration of Action: Tresiba provides a long duration of insulin action, lasting up to 42 hours, which allows for flexible dosing schedules and reduces the need for multiple daily injections.
• Stable Blood Glucose Control: Its ultra-long-acting profile helps in achieving stable blood glucose levels with minimal fluctuations, contributing to better overall glycemic control.
• Reduced Risk of Hypoglycemia: Tresiba’s flat and predictable action profile lowers the risk of nighttime hypoglycemia compared to other insulin formulations.
• Flexibility in Dosing Time: The long duration of action means that Tresiba can be administered at any time of the day, making it easier to fit into varying daily routines without compromising effectiveness.
• Convenient Administration: The prefilled pen format simplifies the injection process, making it easier for patients to administer their insulin doses accurately.

Side Effects of Tresiba 100 Units/ml Penfill (3ml Each)

Like all medications, Tresiba may cause side effects, although not everyone will experience them. Common side effects include:

• Hypoglycemia: The most common side effect of insulin therapy is low blood sugar. Symptoms may include shakiness, dizziness, sweating, confusion, and irritability. Severe hypoglycemia can lead to loss of consciousness or seizures.
• Injection Site Reactions: Some patients may experience redness, swelling, or itching at the injection site.
• Weight Gain: Insulin therapy can lead to weight gain, which may be due to improved appetite and increased fat storage.
• Allergic Reactions: Rarely, patients may experience allergic reactions such as rash, itching, or difficulty breathing. Severe allergic reactions are uncommon but require immediate medical attention.
• Lipodystrophy: Repeated injections at the same site can lead to changes in the fat tissue (lipodystrophy) which can affect insulin absorption.

FAQ

Q: How often should Tresiba be administered?
A: Tresiba is usually administered once daily. The exact time of administration can be adjusted according to the patient’s schedule, but it should be taken around the same time each day to maintain stable blood glucose levels.

Q: Can Tresiba be used in combination with other insulin types?
A: Yes, Tresiba is often used in combination with rapid-acting or short-acting insulins to manage blood glucose levels more effectively, especially in type 1 diabetes or in patients with type 2 diabetes who require additional insulin coverage.

Q: What should I do if I miss a dose of Tresiba?
A: If a dose is missed, it should be taken as soon as possible. If it is almost time for the next dose, skip the missed dose—do not double up to make up for a missed dose. Consult your healthcare provider for specific instructions.

Q: How should Tresiba be stored?
A: Unopened Tresiba Penfill should be stored in the refrigerator (2°C to 8°C or 36°F to 46°F). Once in use, it can be stored at room temperature (up to 30°C or 86°F) for up to 8 weeks. Do not freeze or expose to extreme temperatures.

Q: Are there any contraindications for using Tresiba?
A: Tresiba should not be used in individuals who have a known hypersensitivity to insulin degludec or any of the other ingredients in the formulation. It should be used with caution in patients with severe liver or kidney impairment.

Q: What should I do if I experience severe side effects?
A: If you experience severe symptoms such as severe hypoglycemia, severe allergic reactions, or any other unusual symptoms, seek immediate medical attention.

Disclaimer

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