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Udapa-M 10/500 XR Tablet

Original price was: ₹145.30.Current price is: ₹130.77.

Prescription Required

Salt : Dapagliflozin (10mg) + Metformin (500mg) + Vildagliptin (100mg)

Manufacturer : USV Ltd

Packing : 10 tablet er in 1 strip

Description

PRODUCT INTRODUCTION

Udapa-M 10/500 XR Tablet is a combination medication primarily used for the management of type 2 diabetes mellitus. This extended-release formulation contains two active ingredients: Dapagliflozin and Metformin Hydrochloride. Dapagliflozin is an inhibitor of sodium-glucose co-transporter 2 (SGLT2), while Metformin is a biguanide. Together, these ingredients work synergistically to improve glycemic control in adults with type 2 diabetes.

Dapagliflozin helps lower blood sugar levels by preventing glucose reabsorption in the kidneys, leading to its excretion through urine. Metformin works by decreasing hepatic glucose production, reducing intestinal absorption of glucose, and enhancing insulin sensitivity. This dual-action helps in achieving better blood sugar control than when either of the components is used alone.

Udapa-M 10/500 XR Tablet is often prescribed when diet and exercise alone do not provide adequate glycemic control, and it is suitable for use alongside other diabetes medications.

USES OF Udapa-M 10/500 XR Tablet

Udapa-M 10/500 XR Tablet is primarily used to:

  • Improve glycemic control in adults with type 2 diabetes mellitus.
  • Reduce the risk of cardiovascular events in patients with type 2 diabetes and established cardiovascular disease.
  • Aid in weight loss and improve overall metabolic health due to the combined effects of dapagliflozin and metformin.

BENEFITS OF Udapa-M 10/500 XR Tablet

The combination of dapagliflozin and metformin in Udapa-M 10/500 XR Tablet offers several benefits:

  1. Enhanced Blood Sugar Control: By combining two different mechanisms of action, the medication provides a more comprehensive approach to managing blood glucose levels.
  2. Cardiovascular Protection: Dapagliflozin has been shown to reduce the risk of heart failure and other cardiovascular events in patients with type 2 diabetes, offering additional benefits beyond glycemic control.
  3. Weight Management: Dapagliflozin promotes the excretion of glucose in urine, which can result in a reduction in body weight. This is particularly beneficial for overweight or obese patients with type 2 diabetes.
  4. Lower Risk of Hypoglycemia: Unlike some other diabetes medications, dapagliflozin and metformin do not typically cause hypoglycemia (low blood sugar) when used alone. This makes it a safer option for many patients.
  5. Improved Insulin Sensitivity: Metformin improves the body’s sensitivity to insulin, helping to manage insulin resistance, a common issue in type 2 diabetes.

SIDE EFFECTS OF Udapa-M 10/500 XR Tablet

While Udapa-M 10/500 XR Tablet is generally well-tolerated, it may cause some side effects. Common side effects include:

  1. Gastrointestinal Issues: Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite are common, especially during the initial phase of treatment with metformin.
  2. Genital Infections: Dapagliflozin can increase the risk of genital fungal infections in both men and women due to the higher glucose concentration in urine.
  3. Urinary Tract Infections: An increased risk of urinary tract infections is associated with dapagliflozin.
  4. Dehydration: Due to increased urination, there is a risk of dehydration, particularly in the elderly or those taking diuretics.
  5. Lactic Acidosis: Though rare, metformin can cause a serious condition known as lactic acidosis, particularly in patients with kidney issues or other risk factors.

FAQ

  • How should Udapa-M 10/500 XR Tablet be taken?
    • Udapa-M 10/500 XR Tablet should be taken as prescribed by your healthcare provider, usually once daily with meals to reduce the risk of gastrointestinal side effects. Swallow the tablet whole; do not crush or chew it.
  • Can Udapa-M 10/500 XR Tablet be taken with other diabetes medications?
    • Yes, Udapa-M 10/500 XR Tablet can be used in combination with other diabetes medications, such as insulin or sulfonylureas, but always under the guidance of a healthcare provider.
  • What should I do if I miss a dose?
    • If you miss a dose of Udapa-M 10/500 XR Tablet, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for the missed one.
  • Are there any dietary restrictions while taking Udapa-M 10/500 XR Tablet?
    • While taking this medication, it is essential to follow a healthy diet as advised by your healthcare provider. Limiting alcohol intake is crucial as it can increase the risk of lactic acidosis with metformin.
  • Can Udapa-M 10/500 XR Tablet cause weight gain?
    • No, Udapa-M 10/500 XR Tablet is more likely to aid in weight loss due to the glucose excretion effect of dapagliflozin.
  • Is Udapa-M 10/500 XR Tablet safe during pregnancy?
    • The safety of Udapa-M 10/500 XR Tablet during pregnancy has not been established. It is essential to discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
  • Can I drive or operate machinery while taking Udapa-M 10/500 XR Tablet?
    • Generally, Udapa-M 10/500 XR Tablet does not affect your ability to drive or operate machinery. However, if you experience dizziness or other side effects, refrain from these activities and consult your healthcare provider.

References

  1. Dapagliflozin and metformin HCl extended-release. Wilmington, Delaware: AstraZeneca Pharmaceuticals LP; 2014 [revised Jul. 2017]. [Accessed 29 Apr. 2019] (online) Available from:External Link
  2. Dapagliflozin + Metformin. Södertälje, Sweden: AstraZeneca; 2014. [Accessed 25 Apr. 2019] (online) Available from:External Link
  3. Dapagliflozin and metformin hydrochloride. [Summary of Product Characteristics]. Södertälje, Sweden: AstraZeneca AB; 2021. [Accessed 13 Oct. 2021] (online) Available from:External Link
  4. Dapagliflozin and metformin hydrochloride tablets [Product monograph]. Mississauga, Ontario; AstraZeneca Canada Inc.; 2020. [Accessed 13 Oct. 2021] (online) Available from:External Link
  5. Medscape. Dapagliflozin+Metformin. [Accessed 25 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organization. Dapagliflozin+Metformin. [Accessed 28th Sept. 2023] (online) Available from: External Link
  7. Dapagliflozin and metformin [Summary of Product Characteristics]. Södertälje, Sweden: AstraZeneca AB; 2018. [Accessed 28th Sept. 2023] (online) Available from: External Link
  8. European Medicine Agency. Xigduo (dapagliflozin / metformin). [Accessed 28th Sept. 2023] (online) Available from: External Link

Disclaimer

Singhla Medicos’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Singhla Medicos. Our mission is to support, not replace, the doctor-patient relationship.

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